Design and implementation of fluidic micro-pulleys for flow control on centrifugal microfluidic platforms.

Microfluidic discs have been employed in a variety of applications for chemical analyses and biological diagnostics. These platforms offer a sophisticated fluidic toolbox, necessary to perform processes that involve sample preparation, purification, analysis, and detection. However, one of the weaknesses of such systems is the uni-directional movement of fluid from the disc center to its periphery due to the uni-directionality of the propelling centrifugal force.

Theoretical development and critical analysis of burst frequency equations for passive valves on centrifugal microfluidic platforms.

This paper presents a theoretical development and critical analysis of the burst frequency equations for capillary valves on a microfluidic compact disc (CD) platform. This analysis includes background on passive capillary valves and the governing models/equations that have been developed to date. The implicit assumptions and limitations of these models are discussed.