Chapter 6: SYNDROMIC PRIMARY HYPERPARATHYROIDISM.

Syndromic primary hyperparathyroidism has several features in common: younger age at diagnosis when compared with sporadic primary hyperparathyroidism, often synchronous or metachronous multi-glandular involvement, higher possibility of recurrence, association with other endocrine or extra-endocrine disorders, and suggestive family background with autosomal dominant inheritance. Hyperparathyroidism in multiple endocrine neoplasia type 1 is the most common syndromic hyperparathyroidism. It is often asymptomatic in adolescents and young adults, but may be responsible for recurrent lithiasis and/or bone loss.

Trigeminal neuralgia improvement following Transcutaneous Electrical Nerve Stimulation (TENS): a systematic review and meta-analysis.

Background: Trigeminal neuralgia (TN) is a prevalent and debilitating craniofacial pain disorder characterized by severe, unilateral, shock-like pain. Standard treatments include anti-epileptic drugs and surgical interventions, but many patients experience limited relief or adverse effects. Non-invasive therapies, such as transcutaneous electrical nerve stimulation (TENS), have emerged as alternative options.

Talent management intervention towards performance outcomes of Jordanian telecommunication companies: mediating role of perceived organizational support.

Background: Grounding on the Resource-Based View (RBV) and organization support theory (OST), this study examines the effect of talent management practice (TMP) on perceived organizational support (POS), organizational performance (OP), and employee performance (EP) within the Jordanian telecom sector, with a specific focus on the mediating effect of POS's between TMP-EP and OP relationship.

Methods: This study uses a cross-sectional method to collect data from 397 personnel at three Jordanian telecom enterprises. The Smart-PLS application assisted with structural equation modeling, which was used to examine the data.

Gastrointestinal Sequelae of COVID-19: Investigating Post-Infection Complications-A Systematic Review.

Gastrointestinal (GI) complications are significant manifestations of COVID-19 and are increasingly being recognized. These complications range from severe acute pancreatitis to colitis, adding complexity to diagnosis and management. A comprehensive database search was conducted using several databases.

Effects of extracellular metabolic acidosis and out-of-equilibrium CO/HCO solutions on intracellular pH in cultured rat hippocampal neurons.

Metabolic acidosis (MAc)-an extracellular pH (pH) decrease caused by a [HCO ] decrease at constant [CO]-usually causes intracellular pH (pH) to fall. Here we determine the extent to which the pH decrease depends on the pH decrease vs the concomitant [HCO ] decrease. We use rapid-mixing to generate out-of-equilibrium CO/HCO solutions in which we stabilize [CO] and [HCO ] while decreasing pH (pure acidosis, pAc), or stabilize [CO] and pH while decreasing [HCO ] (pure metabolic/down, pMet↓).

Correction: Neubert et al. Effects of Normobaric Hypoxia and Adrenergic Blockade over 72 h on Cardiac Function in Rats. 2023, , 11417.

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Congenital and acquired hypothyroidism: Temporal and spatial trends in France from 2014 to 2019.

Purpose: To assess the incidence of congenital hypothyroidism (CH) and acquired hypothyroidism (AH) between 2014 and 2019 in continental France.

Methods: New cases of CH and AH were identified using the French National Health Data System (Système Nationale des Données de Santé, SNDS). Temporal trends were studied using linear regression models.

Hypoxia-Induced Pulmonary Injury-Adrenergic Blockade Attenuates Nitrosative Stress, and Proinflammatory Cytokines but Not Pulmonary Edema.

Hypoxia can induce pulmonary edema (PE) and inflammation. Furthermore, hypoxia depresses left ventricular (LV) inotropy despite sympathetic activation. To study the role of hypoxic sympathetic activation, we investigated the effects of hypoxia with and without adrenergic blockade (AB) on cardiovascular dysfunction and lung injury, i.

Panic disorder during pregnancy: A scoping review.

Background: Panic Disorder is a serious anxiety disorder, and one of the severe mental problems that impacts mothers' mental health and fetal health as well.

Aim: The current scoping review aims to provide a wide overview of the literature regarding panic disorder during pregnancy.

Methods: Twenty-five eligible articles were selected for full review from SAGE, CINAHL, PubMed, Medline, Research Gate, Science Direct, and Google Scholar literature searches.

Farming activity and risk of treated thyroid disorders: Insights from the TRACTOR project, a nationwide cohort study.

Background: Epidemiological data regarding thyroid diseases are lacking, in particular for occupationally exposed populations.

Objectives: To compare the risk of hypothyroidism and hyperthyroidism between farming activities within the complete population of French farm managers (FMs).

Methods: Digital health data from retrospective administrative databases, including insurance claims and electronic health/medical records, was employed.

Selective vulnerability of hippocampal CA1 and CA3 pyramidal cells: What are possible pathomechanisms and should more attention be paid to the CA3 region in future studies?

Transient ischemia and reperfusion selectively damage neurons in brain, with hippocampal pyramidal cells being particularly vulnerable. Even within hippocampus, heterogeneous susceptibility is evident, with higher vulnerability of CA1 versus CA3 neurons described for several decades. Therefore, numerous studies have focused exclusively on CA1.

Predicting m-health acceptance from the perspective of unified theory of acceptance and use of technology.

Addressing the growing popularity of mobile health (m-Health) technology in the health industry, the current study examined consumers' intention and behaviour related to the usage of digital applications based on the unified theory of acceptance and use of technology (UTAUT). In particular, this study quantitatively assessed the moderating role of perceived product value and mediating role of intention to use m-Health application among Indonesians. This study adopted a cross-sectional design and collected quantitative data from conveniently selected respondents through an online survey, which involved 2068 Telegram users in Indonesia.

Modelling the mass adoption potentials of eBikes among Malaysian youth.

This study examined (1) the effect of environmental concern, environmental knowledge, and health consciousness on attitude towards eBikes; (2) the effect of eBikes attributes of interest and infrastructure on perceived behavioural control; and finally, (3) the effect of attitude towards eBikes, subjective norms, and perceived behavioural control on eBikes commuting intention and its usage among Malaysian youth. This study adopted a cross-sectional design and convenience sampling, and collected quantitative data from 699 Malaysian youth through an online survey. Findings revealed that (1) environmental concern, environmental knowledge, and health consciousness had a positive and significant impact on attitude towards eBikes; (2) eBikes attributes of interest and infrastructure were positively and significantly related to perceived behavioural control; (3) attitude towards eBikes, subjective norms, and perceived behavioural control had a positive and significant effect on eBikes commuting intention; (4) eBikes commuting intention was positively and significantly related to the usage of eBikes; (5) eBikes commuting intention significantly mediated the relationship between attitude towards eBikes and perceived behavioural control on the usage of eBikes among Malaysian youth; and (6) eBikes commuting intention did not mediate the relationship between social norm and usage of eBikes.

Effects of Normobaric Hypoxia and Adrenergic Blockade over 72 h on Cardiac Function in Rats.

In rats, acute normobaric hypoxia depressed left ventricular (LV) inotropic function. After 24 h of hypoxic exposure, a slight recovery of LV function occurred. We speculated that prolonged hypoxia (72 h) would induce acclimatization and, hence, recovery of LV function.

Leadership, capability and performance: A study among private higher education institutions in Indonesia.

Higher education institution is an important sector to obtain capabilities for global challenges. This study explored the mediating effect of ambidextrous capability between the link organizational leadership capability, learning orientation, and strategic flexibility on the performance of private higher education institutions in Indonesia. In this cross-sectional study, an online survey, which involved 524 rectors or deans in private higher education institutions (HEIs), was conducted using Google Forms.

Evaluation of waste management and energy saving for sustainable green building through analytic hierarchy process and artificial neural network model.

A significant portion of the solid waste filling landfills worldwide is debris from construction and demolition projects. Across the world, a significant portion of the solid waste filling landfills is made up of construction and demolition waste. Recycling construction waste may help cut down on the quantity of waste sent to landfills and the requirement for energy and other natural resources.

Thyrotropin Levels in Patients with Coronavirus Disease 2019: Assessment during Hospitalization and in the Medium Term after Discharge.

Background: The objectives of this study were (1) to compare TSH levels between inpatients with critical versus non-critical coronavirus disease 19 (COVID-19), and (2) to describe the status of TSH levels three months after hospitalization.

Methods: We collected data on adult patients hospitalized with COVID-19 at Amiens University Hospital. We compared TSH levels between inpatients with critical (intensive care unit admission and/or death) versus non-critical COVID-19.

Perigestational exposure of a combination of a high-fat diet and pesticide impacts the metabolic and microbiotic status of dams and pups; a preventive strategy based on prebiotics.

Purpose: Metabolic changes during the perinatal period are known to promote obesity and type-2 diabetes in adulthood via perturbation of the microbiota. The risk factors for metabolic disorders include a high-fat diet (HFD) and exposure to pesticide residues. The objective of the present study was to evaluate the effects of perigestational exposure to a HFD and chlorpyrifos (CPF) on glycemia, lipid profiles, and microbial populations in Wistar dams and their female offspring.

An intention to use mobile applications for medical supplies and equipment ordering in clinics.

This research developed a mobile medical supplies and equipment ordering app (MMSEOA) model and attempted to validate it empirically. When customers (clinic doctors) make purchases on the app, two types of reasons can be identified: "reasons for" include enduring involvement (emotions), product description, and awareness (familiarity) while the "reasons against", were demonstrated as perceived risk and resistance to change (fear). This study aimed to strengthen and illuminate the most significant dimensions that enhance a doctor's understanding of MMSEOA and the intention to use it.

Socio-economic determinants of subjective wellbeing toward Sustainable Development Goals: An insight from a developing country.

One of the goals of happiness research is to identify the key factors that influence it. Therefore, the present research is designed to examine the determining factors of subjective wellbeing (SWB) in Pakistan. The present research is conducted by collecting the data of 1,566 households in Punjab, Pakistan, using the ordered logit and tobit model.

Diabetes and cardiovascular risk according to sex: An overview of epidemiological data from the early Framingham reports to the cardiovascular outcomes trials.

Male sex is a major cardiovascular risk factor in the general population, with men showing higher age-adjusted prevalence of cardiovascular disease than women. Diabetes, another major cardiovascular risk factor, affects cardiovascular risk differentially between men and women. Data from prospective observational studies showed that women with diabetes had greater relative risk of cardiovascular events than men with diabetes, leading to a smaller difference between diabetic men and women than between non-diabetic men and women in terms of cardiovascular disease.