Introduction: Spontaneous rupture of the spleen (SPR) is a rare and severe affection, difficult to diagnose, with multiple causes such as: Infectious and hematologic affections which represent more than half of the cases. Among this subset of patients, acute myeloid leukemia is one of the causes.
Presentation Of Case: A 48-year-old man undergoing chemotherapy for acute myeloid leukemia presented with acute intense abdominal pain.