Publications by authors named "Salahddin Gehani"

Clinical trials have demonstrated conclusively the non-inferiority of breast-conserving surgery followed by breast radiation therapy (BCT) compared with mastectomy for the treatment of early-stage invasive breast cancer (BC). The definition of the required surgical margin to ensure adequate removal of the cancer by BCT to obtain an acceptable low local recurrence (LR) rate remains controversial. Meta-analyses published by Houssami et al.

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Intercostal lipomas are rare benign tumors that predominantly occur in the subcutaneous tissue. However, intramuscular intercostal lipomas are exceedingly uncommon and pose diagnostic challenges due to their atypical presentation. Here, we present a case report of an intramuscular intercostal lipoma located in the left axillary tail, along with a comprehensive discussion of its clinical features, diagnostic evaluation, and management options.

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Article Synopsis
  • Patients with triple-negative breast cancer (TNBC) who achieve a pathological complete response (pCR) have significantly better outcomes than those with residual disease (RD), highlighting the need for effective biomarkers.
  • A study identified a gene panel consisting of eight RD-derived genes that predict both RD and pCR, showing strong correlation with overall survival and relapse-free survival in larger breast cancer cohorts.
  • Further analysis demonstrated that depleting these genes in TNBC cell models inhibited proliferation, and the identified gene signatures could potentially improve clinical decision-making by accurately distinguishing between RD and pCR in patients.
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Human papillomavirus (HPV) has been implicated in the etiology of a variety of human cancers. Studies investigating the presence of high-risk (HR) HPV in breast tissue have generated considerable controversy over its role as a potential risk factor for breast cancer (BC). This is the first investigation reporting the prevalence and type distribution of high-risk HPV infection in breast tissue in the population of Qatar.

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BACKGROUND Peritoneal loose bodies, also known as peritoneal mice, are rare findings and they present either with nonspecific symptoms or are found incidentally during exploration and autopsy. Usually, they have no clinical significance and require no specific treatment. We report a case of a giant peritoneal loose body found incidentally in the abdominal cavity of a patient who presented with abdominal pain and hematuria.

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