Publications by authors named "Salah Omer"

A 50-year-old previously healthy male presented with fever and cough for seven days, positive for COVID-19, and was admitted to Hazm Meberik General Hospital and treated as a case of severe COVID-19 pneumonia. After improvement, he was transferred to a quarantine facility, and he later developed bilateral hemopneumothorax requiring bilateral chest tubes. High-resolution CT showed bilateral emphysematous bullous disease.

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Anti-Ma2 encephalitis is a paraneoplastic disorder characterised by brainstem and/or limbic involvement. Eye movement abnormalities can occur in this condition, often with confusion or somnolence. We describe a patient with progressive oscillopsia (with upbeat nystagmus) and unsteadiness, followed by acute pancreatitis.

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Article Synopsis
  • The text discusses several types of progressive myoclonus epilepsies, focusing on Lafora disease, which has a distinct progression starting in the teenage years and leads to severe neurological decline and death within a decade.
  • Lafora bodies, unique to this disease, are formed from malfunctioning glycogen molecules due to mutations in the EPM2A and EPM2B genes, which affect the enzymes responsible for proper glycogen structure and solubility.
  • A newly identified early-onset Lafora body disease has been mapped to chromosome 4q21.21, with a mutation in the PRDM8 gene, presenting symptoms at age 5 and creating a disease trajectory that is prolonged compared to typical Lafora disease,
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A 42-year-old man presented with a 3 day history of drooping of the right eyelid and intermittent double vision. He was found to have mechanical restriction of the left eye in elevation and MRI demonstrated an abnormality in the left maxillary sinus with descent of the left inferior rectus muscle. CT confirmed the diagnosis of 'imploding antrum' or 'silent sinus' syndrome.

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Background: Pathogenic mutations of the human mitochondrial genome are associated with well-characterized, progressive neurological syndromes, with mutations in the transfer RNA genes being particularly prominent.

Objective: To describe a novel mitochondrial transfer RNA(Pro) gene mutation in a woman with a myoclonic epilepsy with ragged-red fibers-like disease. Design, Setting, and Patient Case report of a 49-year-old woman presenting with a myoclonic epilepsy with ragged-red fibers-like disease comprising myoclonic jerks, cerebellar ataxia, and proximal muscle weakness.

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Patients presenting with subacute amnesia are frequently seen in acute neurological practice. Amongst the differential diagnoses, herpes simplex encephalitis, Korsakoff's syndrome and limbic encephalitis should be considered. Limbic encephalitis is typically a paraneoplastic syndrome with a poor prognosis; thus, identifying those patients with potentially reversible symptoms is important.

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