Genotypic and phenotypic differences between nodal and extranodal diffuse large B-Cell lymphomas.

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of diseases that have diverse clinical, pathological, and biological features. Here, it is shown that primary nodal and extranodal DLBCLs differ genomically and phenotypically. Using conventional comparative genomic hybridization (CGH), the authors assessed the chromosomal aberrations in 18 nodal, 13 extranodal, and 5 mixed DLBCLs.

Radiotherapy for early stage of Hodgkin's disease at Kuwait Cancer Control Center, Kuwait.

Objective: To evaluate the outcome of using radiotherapy (RT) alone to treat patients with early-stage Hodgkin's disease (HD).

Method: The records of 28 patients with HD treated with RT alone at Kuwait Cancer Control Center between 1980 and 1998 were reviewed.

Results: Twenty-three patients had stage I HD and 5 stage II.