Adult-onset recurrent respiratory papillomatosis: a review of disease pathogenesis and implications for patient counseling.

Importance: A new diagnosis of adult-onset recurrent respiratory papillomatosis (AO-RRP) prompts many questions related to disease acquisition, course, and transmission. Recent attention to the human papillomavirus (HPV), along with emerging data on AO-RRP, provides a foundation for patient counseling.

Objective: To provide a framework for these discussions, including an overview of the current literature on HPV-mediated disease across organs.

Modalities of treatment for laryngotracheal stenosis: the EVMS experience.

Objectives/hypothesis: The aims of the study were to identify trends in surgical management of laryngotracheal stenosis (LTS) based on lesion location, as well as to recognize factors associated with recurrence and repeat surgical intervention.

Study Design: The study is a retrospective review of all adult patients cared for at a tertiary care laryngology practice with a diagnosis of laryngotracheal stenosis between October 2001 and July 2010, following Institutional Review Board approval.

Methods: This study collectively measured demographics, comorbidities, etiologies, sites of stenoses, treatment modalities, and recurrences.