Varicella-zoster virus can be transmitted transplacentally to a fetus from symptomatic mothers developing skin lesions between 5 days before and 2 days after delivery. The diagnosis is clinical. Its management is challenging in limited-resource countries, namely Cambodia, due to the lack of varicella zoster immune globulin and intravenous acyclovir.
View Article and Find Full Text PDFClin Case Rep
October 2024
Although Cambodia is a dengue-endemic country, mother-to-child transmission of dengue virus has yet to be documented. We report a rare case for congenital dengue diagnosed by RT-PCR in a 4-day-old neonate with ascites. The neonate was initially treated for suspected perinatal infection.
View Article and Find Full Text PDFDue to the lack of public awareness, congenital hypothyroidism (CH) remains an overlooked challenge in Cambodia. This disease should be screened routinely at birth because, though asymptomatic, it can lead to mental retardation in the absence of early treatment. Since 2013, our unit has been the only centre that implements routine screening and provides treatment and follow-up.
View Article and Find Full Text PDFChikungunya, a mosquito-borne disease, is posing threat to neonatal population in Cambodia because of its challenging diagnosis and insufficient attention compared with Dengue. In what follows, we present a case of serologically-confirmed congenital chikungunya in a newborn presenting early-onset sepsis, and the mother was underdiagnosed with intrapartum flu-like infection.
View Article and Find Full Text PDF, the most predominant human oral microbiota, is rarely associated with neonatal sepsis. This report aims to describe a rare culture-proven case of early-onset sepsis in a 3-day-old boy with isolated high-grade fever. was isolated in two consecutive hemocultures and unexpectedly resistant to the conventional empirical antibiotics.
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February 2022
BMJ Case Rep
November 2021
The most common cause of congenital heart block (CHB) is neonatal lupus, an acquired autoimmune disease caused by transplacental transfer of maternal antibodies to the fetus. A full-term female neonate was admitted to neonatal intensive care unit for severe bradycardia with stable haemodynamics. The mother, showing no clinical symptoms or any particular history, was transferred to our tertiary centre for profound fetal bradycardia.
View Article and Find Full Text PDFCase Rep Infect Dis
July 2021
Introduction: Syphilis is a tropical disease, caused by a spirochete , which can be transmitted transplacentally from untreated mothers to the fetus during any stages of pregnancy. Clinical manifestations of early congenital syphilis are variable and nonspecific. The diagnosis is based on the serology status of the mother, newborn clinical symptoms, and comparative serology titer between mother and newborn.
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