Changing etiological spectrum of acute liver failure.

Background And Objectives: Acute liver failure (ALF) is an uncommon but potentially dramatic syndrome characterized by massive hepatic necrosis and has a very high mortality rate of 50% to 75% without liver transplantation. This study is aimed at analyzing the etiological spectrum of ALF patients and compare these with ALF mimics such as malaria, dengue fever and other tropical infectious diseases.

Methods: The study population included patients who presented with ALF and ALF mimics in a tertiary care center over two years.