Publications by authors named "Sakina K Khaku"
Article Synopsis
- In response to DNA damage, cells activate two key processes: recognizing and repairing the damage, and temporarily halting the cell cycle for repair to take place.
- The protein complex Replication Protein A (RPA), particularly its 32-kDa subunit RPA2, plays a crucial role in the DNA-damage response, with focus on the N-terminal phosphorylation domain.
- Research using budding yeast showed that while the Rfa2 N-terminus is important for responding to DNA damage, its phosphorylation isn't necessary; however, modifications might affect whether cells continue dividing amidst unrepaired damage.
