Periodontal inflammation triggers a site-specific and wide radius of calcium metabolic effects on alveolar bone.

Background And Objective: There is a close relationship between inflammation and bone remodeling in the periodontium. However, previous studies have not delineated the alterations in calcium (Ca) metabolism during periodontitis progression. The aim of this current investigation was to examine Ca dynamics in alveolar bone of rats during progression of ligature-induced periodontal inflammation by using Ca, which is an index of hard tissue neogenesis.

Temporal and dynamic changes in gingival blood flow during progression of ligature-induced periodontitis.

Objectives: To evaluate temporal changes in gingival blood flow (GBF) during progression of periodontitis in rats using a laser Doppler flowmeter (LDF) approach and to characterize morphological and biochemical features in the periodontium associated with GBF.

Materials And Methods: Forty-two Wistar rats were divided into a ligature-induced periodontitis group and a control group. To induce periodontitis, ligatures were tied around maxillary first molars bilaterally.