Publications by authors named "Sakhi Abraham"
Article Synopsis
- Researchers are exploring the use of broad neutralizing antibodies (bNAbs) to create effective vaccines against HIV-1, focusing on antibodies that target conserved parts of the virus, which is crucial for protection against different strains.
- The study involved designing an HIV vaccine that includes molecular adjuvants, BAFF and APRIL, to enhance the body's ability to produce effective antibodies by maturing B cells and increasing the strength of the immune response.
- The findings demonstrated that vaccination with these adjuvants, particularly when boosted with protein, successfully prompted the production of neutralizing antibodies in mice without causing excessive B cell expansion, indicating a promising path for developing effective HIV vaccines.
