Anti-Neuroinflammatory Potential of Areca Nut Extract and Its Bioactive Compounds in Anthracene-Induced BV-2 Microglial Cell Activation.

Particulate matter (PM) containing polycyclic aromatic hydrocarbons (PAHs) is of considerable environmental importance worldwide due to its adverse effects on human health, which are associated with neurodegenerative diseases (NDDs). L. (AC) fruit is known to possess various pharmacological properties; however, the anti-neuroinflammatory roles of AC on the suppression of PAH-induced neuroinflammation are still limited.

var. Berry Seed Protects against TNF-α-Stimulated Neuroinflammation by Inducing HO-1 and Suppressing NF-κB Mechanism in BV-2 Microglial Cells.

Sustained inflammatory responses have been implicated in various neurodegenerative diseases (NDDs). var. (CN), an indigenous berry, has been reported to exhibit several health-beneficial properties.

Beyond the classical amyloid hypothesis in Alzheimer's disease: Molecular insights into current concepts of pathogenesis, therapeutic targets, and study models.

Alzheimer's disease (AD) is one of the progressive neurodegenerative disorders and the most common cause of dementia in the elderly worldwide causing difficulties in the daily life of the patient. AD is characterized by the aberrant accumulation of β-amyloid plaques and tau protein-containing neurofibrillary tangles (NFTs) in the brain giving rise to neuroinflammation, oxidative stress, synaptic failure, and eventual neuronal cell death. The total cost of care in AD treatment and related health care activities is enormous and pharmaceutical drugs approved by Food and Drug Administration have not manifested sufficient efficacy in protection and therapy.

Anti-neuroinflammatory effects of var. berry-seed extract in BV-2 microglial cells via inhibition of MAPKs/NF-κB signaling pathway.

Neuroinflammation is an essential contributor to multiple neurodegenerative disorders. var. , an edible berry, has been reported to exhibit a neuroprotective effect.

Potential Anti-Diabetic Activity of Flower (Flos Puerariae) Extracts.

(Wild.) Ohwi. () flowers known as 'Kudzu flower' contain isoflavonoids and essential oil components.