Publications by authors named "Sakai Osamu"

Various new dental treatment methods have been introduced in dental clinics, and many new materials have been used in recent years for dental treatments. Dentistry is divided into several specialties, each offering unique treatments, such as endodontics, implantology, oral surgery, and orthodontics. CT and MR images after dental treatment reveal a variety of hard- and soft-tissue changes and dental materials, which often cause image artifacts.

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Background And Purpose: Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) are the most common causes of chronic sinusitis from systemic granulomatous diseases. While both are small- to medium-sized vasculitis with necrotizing granulomas, they have different clinical courses and prognoses. High-density sinus opacification has been reported in allergic fungal sinusitis with eosinophilic infiltrates.

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Article Synopsis
  • Percutaneous balloon ganglyolysis (PBG) is an effective, low-cost, and minimally invasive treatment for trigeminal neuralgia (TN), with 42.3% of patients experiencing immediate pain resolution.
  • A study analyzed 52 TN patients who underwent 83 PBG procedures, identifying that 30.8% required retreatment after a median of 32 months, with significant predictors for retreatment being TN duration of ≤ 6 months.
  • Findings suggest that understanding TN duration may help inform treatment strategies, highlighting the need for further research to validate these results.
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Only a limited number of tumour biomarkers are currently available in veterinary medicine, particularly in cats. Cell-free DNA (cfDNA) is an extracellular DNA fragment released upon cell death and is considered a minimally invasive biomarker for the diagnosis and monitoring of various human malignancies. This study aimed to clarify the utility of circulating cfDNA as a liquid biopsy for various feline tumours.

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Purpose: The literature on skull base chondrosarcoma (CHS) is scarce. We report outcomes for pediatric and young patients ≤22 years with base of skull CHSs treated with proton-based radiation therapy (PBRT).

Methods And Materials: We retrospectively reviewed all patients treated with PBRT between 1981 and 2023.

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Trace elements and stable isotope ratios in otoliths have been used as proxies for the migration history of teleosts; however, their application in oceanic fishes remains limited. This study reports the first use of radiocarbons in otoliths to evaluate the horizontal migration histories of an oceanic fish species, the walleye pollock . We conducted radiocarbon analyses of three stocks sourced from Hokkaido, Japan.

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Individual animals exhibit considerable differences in cognitive characteristics associated with personality differences. The cognition-personality link was intensively investigated in the last decade though with mixed results. To grasp the general pattern, a common method should be applied to a wide range of animals.

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Background: Human papillomavirus (HPV) status plays a major role in predicting oropharyngeal squamous cell carcinoma (OPSCC) survival. This study assesses the accuracy of a fully automated 3D convolutional neural network (CNN) in predicting HPV status using CT images.

Methods: Pretreatment CT images from OPSCC patients were used to train a 3D DenseNet-121 model to predict HPV-p16 status.

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Foreign body ingestion is a common clinical occurrence worldwide, with high morbidity in the pediatric population and in adult patients with intentional attempts. Coins and button battery ingestions are more common among children. Bone impaction and swallowed dentures are usually seen in older adults.

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Maze-solving is a classical mathematical task, and is recently analogously achieved using various eccentric media and devices, such as living tissues, chemotaxis, and memristors. Plasma generated in a labyrinth of narrow channels can also play a role as a route finder to the exit. In this study, we experimentally observe the function of maze-route findings in a plasma system based on a mixed discharge scheme of direct-current (DC) volume mode and alternative-current (AC) surface dielectric-barrier discharge, and computationally generalize this function in a reinforcement-learning model.

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Objective: Internal Jugular Vein Stenosis (IJVS) is hypothesized to play a role in the pathogenesis of diverse neurological diseases. We sought to evaluate differences in IJVS assessment between CT and MRI in a retrospective patient cohort.

Methods: We included consecutive patients who had both MRI of the brain and CT of the head and neck with contrast from 1 June 2021 to 30 June 2022 within the same admission.

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Article Synopsis
  • - Left atrial myxoma, a common benign tumor, may grow rapidly despite being known as a "slow-growing" tumor, leading to serious complications when it suddenly enlarges.
  • - A 64-year-old woman with a diagnosed left atrial tumor experienced a rapid change in her tumor's size and shape, accompanied by a sudden decline in her respiratory condition, prompting emergency surgery.
  • - The surgery revealed the myxoma was complicated by multiple internal hemorrhages, highlighting the importance of recognizing the potential risks associated with these tumors, as they can rapidly deteriorate despite their typical slow growth.
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  • The study investigates the effectiveness of machine learning techniques, specifically support vector machine (SVM) and bidirectional Long short-term memory (Bi-LSTM), in accurately detecting parathyroid adenomas among lymph nodes.
  • Using data from 93 4D-CTs and analyzing enhancements, the Bi-LSTM model achieved a higher accuracy (92%) and AUC (0.99) compared to SVM (88% accuracy and AUC of 0.95) on validation data.
  • Results indicate that enhancement characteristics are crucial in distinguishing parathyroid adenomas, with Bi-LSTM statistically outperforming SVM, highlighting the potential of advanced machine learning in medical diagnostics.
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  • HPV status is crucial for understanding prognosis in oropharyngeal cancer (OPC), and this study aimed to use machine learning to improve patient management noninvasively.
  • Researchers developed multi-parametric algorithms based on data from 492 OPC patients, analyzing factors like age, sex, and lifestyle habits to predict both HPV status and survival outcomes.
  • The algorithms demonstrated strong performance, with the best HPV status model achieving 78.7% accuracy and the survival model reaching 87.7% accuracy, indicating the potential of AI to enhance clinical decision-making without invasive procedures.
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Background: Chylothorax after cardiovascular surgery is primarily caused by direct injury to the thoracic duct or its branches, and occurs in early postoperative period. In the present case, we describe a rare case of chylothorax manifesting three months after surgery secondary to constrictive pericarditis.

Case Presentation: A 71-year-old man underwent mitral valve replacement, tricuspid valve annuloplasty, and the maze procedure.

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Objective: To investigate the utility of texture analysis in detecting osseous changes associated with hyperparathyroidism on neck CT examinations compared with control patients and to explore the best regions in the head and neck to evaluate changes in the trabecular architecture secondary to hyperparathyroidism.

Methods: Patients with hyperparathyroidism who underwent a 4D CT of the neck with contrast were included in this study. Age-matched control patients with no history of hyperparathyroidism who underwent a contrast-enhanced neck CT were also included.

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(1) Background: The impairment of eye-hand coordination and smooth-pursuit eye movement caused by visual display terminal (VDT) operation is thought to impair daily living activities, for which no effective methods are currently known. On the other hand, various food ingredients, including astaxanthin, lutein, and zeaxanthin, are known to help improve the eye health of VDT operators. This study aimed to test the hypothesis that the combination of astaxanthin, lutein, and zeaxanthin can prevent the impairment of eye-hand coordination and smooth-pursuit eye movement caused by VDT operation.

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Nocturnal predators of many taxa are known to come to artificial light at night for foraging on clumped food resources. Both innate and acquired light preferences seem to be possible mechanisms of light approaching behavior although empirical tests are lacking in most nocturnal predators. Here, using a Japanese gecko Gekko japonicus, we investigated whether geckos have a light preference and how foraging experiences under the light reinforce light approaching tendency.

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Animals often exhibit consistent-individual differences (CIDs) in boldness/fearfulness, typically studied in the context of predation risk. We focus here on fear generalization, where fear of one danger (e.g.

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Co-Ni alloy nanoparticles, a potential candidate for microwave absorption material, were successfully synthesized by tuning the reduction timing of Co and Ni ions by introducing oleylamine as a complexing agent and 1-heptanol as a reducing solvent. The formation mechanism elucidated using time-resolved sampling and in situ X-ray absorption spectroscopy (XAS) and ultraviolet-visible (UV-vis) spectrophotometry measurements suggested that the delay in the reduction of Co ions via complexation with oleylamine facilitated the co-reduction of Co with Ni ions and led to the formation of Co-Ni alloys. The successful synthesis of Co-Ni alloys experimentally confirmed the differences in magnetic properties between alloy and core-shell structured CoNi particles.

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This review on brain multiparametric quantitative MRI (MP-qMRI) focuses on the primary subset of quantitative MRI (qMRI) parameters that represent the mobile ("free") and bound ("motion-restricted") proton pools. Such primary parameters are the proton densities, relaxation times, and magnetization transfer parameters. Diffusion qMRI is also included because of its wide implementation in complete clinical MP-qMRI application.

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Background Extremely preterm (EP) birth is associated with higher risks of perinatal white matter (WM) injury, potentially causing abnormal neurologic and neurocognitive outcomes. MRI biomarkers distinguishing individuals with and without neurologic disorder guide research on EP birth antecedents, clinical correlates, and prognoses. Purpose To compare multiparametric quantitative MRI (qMRI) parameters of EP-born adolescents with autism spectrum disorder, cerebral palsy, epilepsy, or cognitive impairment (ie, atypically developing) with those without (ie, neurotypically developing), characterizing sex-stratified brain development.

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Background/aim: Chimeric antigen receptor (CAR) T cell therapy targeting CD20 has the potential to become a promising novel treatment for canine B cell lymphoid malignancy. However, the optimal approach for producing potent CAR-T cells with favorable phenotype for dogs remains unknown. In this study, we assessed several culture conditions and their effects on the phenotypic characteristics of CD20-CAR-T cells.

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A is defined as an incidental, often asymptomatic, imaging finding that mimics a true pathologic condition. Given the complex anatomy and wide variety of normal variants in the oral and maxillofacial region, a thorough understanding of commonly encountered normal variants in this region is essential to avoid misinterpretation and unnecessary further imaging or interventions. Moreover, familiarity with normal variants that are known to become symptomatic at times is necessary to facilitate further workup and guide the treatment plan.

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