Publications by authors named "Sakae Hino"

Article Synopsis
  • * In a sample of 67 PD patients previously diagnosed with dopamine transporter scintigraphy, TCS confirmed visibility of the midbrain in 64.1% of patients, while high-signal-intensity lesions were found in 35.8%.
  • * The findings suggest that patients with normal MIBG results may still have significant lesions, indicating that TCS could serve as a valuable diagnostic tool for identifying high-signal-intensity substantia nigra lesions in
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Article Synopsis
  • The study aimed to assess the effectiveness and safety of MR-guided focused ultrasound (MRgFUS) treatment for patients with essential tremor, particularly focusing on those with a low skull density ratio (SDR).
  • Real-world data from 101 patients treated between July 2019 and March 2022 were analyzed, categorizing patients into four quartiles based on their mean SDR and evaluating treatment outcomes, parameters, and adverse events.
  • Results showed that MRgFUS significantly improved tremor severity across all SDR groups, but individuals with very low SDR experienced lower temperature and coagulation volume during treatment, along with more frequent adverse events, which mostly resolved by the 3-month follow-up.
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Article Synopsis
  • The Clinical Rating Scale for Tremor (CRST) is widely used but has limitations like ceiling effects and variability in test results when assessing essential tremor (ET).
  • This study tested videographic motion analysis as a new way to evaluate ET by recording patients performing tasks and analyzing the videos with software.
  • The findings showed that video analysis provided reliable measurements that correlated well with traditional CRST scores and was effective in tracking improvements after focused ultrasound treatment for tremor.
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Article Synopsis
  • A patient with tremor-dominant Parkinson's disease experienced mild cavitation effects during a procedure called magnetic resonance-guided focused ultrasound thalamotomy, which caused temporary speech difficulties and numbness.
  • Despite these issues, the patient's tremor and rigidity improved, and MRI scans showed significant changes in the thalamus after the procedure.
  • Although cavitation can help alleviate symptoms, it requires close monitoring to minimize the risk of lasting adverse effects due to its unpredictable nature.
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Purpose: This study aimed to investigate the accuracy and clinical significance of an artificial intelligence (AI)-based automated Alberta Stroke Program Early Computed Tomography (ASPECT) scoring software of head CT for the indication of intravenous recombinant tissue plasminogen activator (rt-PA) therapy.

Methods: This study included two populations of acute ischemic stroke: one comprised patients who had undergone head CT within 48 h of presentation (Population #1, = 448), while the other included patients within 4.5 h from onset (Population #2, = 132).

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Article Synopsis
  • The study aimed to assess how well a 3D motion-analysis system (AKIRA) can quantify motor symptoms in patients with Parkinson's disease (PD).
  • It involved 48 PD patients who were monitored while walking, measuring various motion parameters and comparing them with established Parkinson's scales.
  • Results indicated that neck and trunk tilt angles related strongly to PD symptom severity, suggesting these measurements could serve as objective indicators for tracking disease progression.
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A 47-year-old man who was previously hospitalized three times due to bacterial meningitis experienced a headache and posterior neck pain in May. He was admitted to our hospital because of a fever 3 h later. He was fully conscious and febrile, with a headache and signs of meningeal irritation.

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