Publications by authors named "Sajid Umar"

Background: Feline respiratory disease complex (FRDC) is a set of illnesses which are primarily associated with different types of viruses and bacteria. There is scarcity of data on pathogens associated with FRDC in China.

Objectives: The primary objective of this study was to investigate the prevalence and dynamics of FRDC pathogens in China.

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  • Feline parvovirus (FPV) is a highly contagious and deadly virus affecting cats, with continued clinical cases in vaccinated populations, prompting a need for research into its genotypes and evolution.
  • The study collected and analyzed 152 rectal swabs from diseased cats, finding FPV DNA in 17 samples, indicating a significant presence of the virus despite vaccination efforts.
  • The research identified a new mutation in the virus and confirmed that the FPV-G1 group is the most common strain in Kunshan, suggesting that more comprehensive investigations are necessary to enhance prevention and treatment strategies.
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  • * Researchers collected swab samples from diseased cats and performed genetic sequencing on key viral genes, finding a 21.5% detection rate of FHV-1 among the samples.
  • * Analysis indicated correlations between age, vaccination status, and environment with FHV-1 positivity, but not with the cats' sex; co-infection with feline calicivirus was also noted in some cases.
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Feline calicivirus (FCV) is a highly contagious virus in cats, which typically causes respiratory tract and oral infections. Despite vaccination against FCV being a regular practice in China, new FCV cases still occur. Antigenic diversity of FCV hinders the effective control by vaccination.

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Background: Human respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection and hospitalization, especially in children. Highly mutagenic nature and antigenic diversity enable the RSV to successfully survive in human population. We conducted a molecular epidemiological study during 2017-2021 to investigate the prevalence and genetic characteristics of RSV.

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The emergence of antibacterial resistance (ABR) is an urgent and complex public health challenge worldwide. Antibiotic resistant genes (ARGs) are considered as a new pollutant by the WHO because of their wide distribution and emerging prevalence. The role of environmental factors in developing ARGs in bacterial populations is still poorly understood.

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  • The dairy and meat industry in Turkey has grown significantly over the last ten years, providing essential animal protein for the population.
  • Viral pathogens pose a major threat to this industry, leading to serious economic losses, so effective cattle health management is necessary to combat these diseases.
  • Implementing disease monitoring, research, and control measures like vaccination and biosecurity is vital for improving cattle health and boosting Turkey's economy through increased exports.
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Background: Pigs are unique reservoirs for virus ecology. Despite the increased use of improved biosecurity measures, pig viruses readily circulate in Chinese swine farms.

Objectives: The main objective of this study was to examine archived swine oral secretion samples with a panel of pan-species viral assays such that we might better describe the viral ecology of swine endemic viruses in Chinese farms.

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Background: Human Adenoviruses (HAdVs) cause a wide array of illnesses in all age groups. They particularly cause frequent morbidity among children. In China, human adenovirus types 3, 4, 7, 11, 14, 21, and 55 have caused at least seven outbreaks since 2000.

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Introduction: Fowl adenovirus can cause important diseases in chickens such as inclusion body hepatitis, hepatitis hydropericardium syndrome, and gizzard erosion and ulceration. Inclusion body hepatitis has been regularly reported from many countries. This is the first case report from Turkey, describing an outbreak of inclusion body hepatitis in broiler farms due to fowl adenovirus-8b (FAdV-8b).

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  • Bovine respiratory infections are a major economic issue for the cattle industry globally, including in Turkey, with Influenza D virus (IDV) potentially contributing to these diseases.
  • A study was conducted to investigate the presence of IDV in cattle across Turkey, particularly in farms with high rates of respiratory disease and calf mortality.
  • Out of 76 samples collected from 12 herds, IDV was identified in three cattle, with genetic analysis revealing a 95% similarity to strains found in Europe and the U.S., underscoring the need for ongoing monitoring of this virus in the Turkish cattle industry.
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Background: Viral diseases are a matter of great concern for poultry farmers in Pakistan. Multiple common viral respiratory diseases (CVRDs) cause huge economic losses in the poultry industry. The prevalence of CVRDs in many countries, including Pakistan, is not clearly understood.

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Avian avulaviruses serotype 1 (abbreviated as APMV-1 for the historical name avian paramyxovirus 1) are capable of infecting a wide spectrum of avian species with variable clinical symptoms and outcomes. Ease of transmission has allowed the virus to spread worldwide with varying degrees of virulence depending upon the virus strain and host species. The emergence of new virulent genotypes from global epizootics, and the year-to-year genomic changes in low and high virulence APMV-1 imply that distinct genotypes of APMV-1 are simultaneously evolving at different geographic locations across the globe.

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Introduction: Dengue is one of the major emerging viral diseases in the world, with dramatic increases in reported cases in the last few decades and annual worldwide occurrence of approximately 390 million infections. It is a highly important mosquito-vectored disease and is a problem in tropical and subtropical areas of the world. The major aim of this study was to clone and express the dengue NS3 gene, in service to its therapeutic importance for the development of stable cell lines.

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  • This study highlights the gap in data regarding co-infections in poultry and aims to address this issue through experimental research.* -
  • Broiler birds were infected with both the H9N2 strain and low pathogenic avian influenza (LPAI) virus to analyze clinical effects, finding that co-infection resulted in increased severity of symptoms and reduced survival rates.* -
  • The results suggest that the presence of one virus may enhance the replication of the other, leading to more severe health impacts for the birds, indicating a need for further understanding of these interactions in poultry disease management.*
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Toxoplasma gondii is a protozoan parasite of veterinary and human public health importance for which birds act as an intermediate host. No information is available about the epidemiology of T. gondii in wild birds of Pakistan.

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Antibiotic resistance in avian pathogenic Escherichia coli (APEC) is a common problem in the Indonesian poultry industry. Zoo birds have been postulated as sentinels, reservoirs, and potential spreaders of antibiotic resistance, although much is still unknown about the strains of zoo birds. Disinfection can reduce the infection burden.

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Respiratory diseases are responsible for major economic losses in poultry farms. While in most cases a single pathogen is not alone responsible for the clinical outcome, the impact of co-infections is not well known, especially in turkeys. The purpose of this study was to assess the possible synergism between Escherichia coli (O78) and low pathogenic avian influenza virus (LPAIV, H6N1), in the turkey model.

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The present study was undertaken to find out the safety levels of fenbendazole in common peafowl. This bird, raised on aviaries and zoos, can be severely parasitized with Ascaridia galli (enteric worms) and Syngamus trachea (gapeworm) along with other parasitic worms. Fenbendazole is a highly effective benzimidazole-class anthelmintic in animals.

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The ability of commercial vaccines H120 and 4/91 to protect against Moroccan-Italy 02 infectious bronchitis virus (Mor-It02) was investigated in specific-pathogen-free (SPF) chickens and commercial broiler chickens. Commercial broiler chicks (Experiment 1) were vaccinated at the hatchery with H120 vaccine at Day 1, and challenged at Day 21 with 10 50% egg-infective dose (EID) of Mor-It02. All chicks were observed daily for clinical signs attributable to Mor-It02 infection during the 10 days postchallenge (pc).

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