J Ayub Med Coll Abbottabad
November 2024
An acute vascular angle between the superior mesenteric artery and the Aorta may compress the third part of the duodenum (SMA Syndrome) and the Left Renal Vein (Renal Nutcracker Syndrome). Usually, patients are young females with a lean stature. Symptoms of outlet obstruction and pelvic congestion syndrome may be present.
View Article and Find Full Text PDFBackground: Modified Radical Mastectomy is associated with significant acute postoperative pain. If this pain is not managed properly most patients will develop chronic post-mastectomy pain, which reduces quality of life. Pectoralis (PECS) block is effective in reducing pain and the consumption of analgesia in the post-operative period.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
July 2024
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View Article and Find Full Text PDFWith the urge to secure and protect digital assets, there is a need to emphasize the immediacy of taking measures to ensure robust security due to the enhancement of cyber security. Different advanced methods, like encryption schemes, are vulnerable to putting constraints on attacks. To encode the digital data and utilize the unique properties of DNA, like stability and durability, synthetic DNA sequences are offered as a promising alternative by DNA encoding schemes.
View Article and Find Full Text PDFBackground: Computational intelligence (CI) based prediction models increase the efficient and effective utilization of resources for wind prediction. However, the traditional recurrent neural networks (RNN) are difficult to train on data having long-term temporal dependencies, thus susceptible to an inherent problem of vanishing gradient. This work proposed a method based on an advanced version of RNN known as long short-term memory (LSTM) architecture, which updates recurrent weights to overcome the vanishing gradient problem.
View Article and Find Full Text PDFPost-transcriptional modifications of RNA play a key role in performing a variety of biological processes, such as stability and immune tolerance, RNA splicing, protein translation and RNA degradation. One of these RNA modifications is m5c which participates in various cellular functions like RNA structural stability and translation efficiency, got popularity among biologists. By applying biological experiments to detect RNA m5c methylation sites would require much more efforts, time and money.
View Article and Find Full Text PDFA COVID-19, caused by SARS-CoV-2, has been declared a global pandemic by WHO. It first appeared in China at the end of 2019 and quickly spread throughout the world. During the third layer, it became more critical.
View Article and Find Full Text PDFWe aimed to determine the pooled prevalence of diabetic foot ulcers in Pakistan. MEDLINE (PubMed), Web of Science, Google scholars, and local databases were systematically searched for studies published up to August 10, 2022, on the prevalence of foot among diabetic patients in Pakistan. Random-effects meta-analysis was used to generate summary estimates.
View Article and Find Full Text PDFAnal Chim Acta
November 2022
Comput Intell Neurosci
June 2022
DNA copy number variation (CNV) is the type of DNA variation which is associated with various human diseases. CNV ranges in size from 1 kilobase to several megabases on a chromosome. Most of the computational research for cancer classification is traditional machine learning based, which relies on handcrafted extraction and selection of features.
View Article and Find Full Text PDFMaize is one of the most important field crops considering its utilization as food, feed, fodder, and biofuel. However, the sustainability of its production is under serious threat of heat and drought stresses, as these stresses could hamper crop growth, causing a significant loss to kernel yield. The research study was carried out at Maize and Millets Research Institute, Yusafwala-Sahiwal for two consecutive spring seasons (2019-20 and 2020-21) under a split-split plot design.
View Article and Find Full Text PDFLicense plate localization is the process of finding the license plate area and drawing a bounding box around it, while recognition is the process of identifying the text within the bounding box. The current state-of-the-art license plate localization and recognition approaches require license plates of standard size, style, fonts, and colors. Unfortunately, in Pakistan, license plates are non-standard and vary in terms of the characteristics mentioned above.
View Article and Find Full Text PDFThe purpose of this investigation was to evaluate the vicissitudes in polyphenolic extract- based high internal phase creams (HIPCs) and effect of storage temperature dependent characteristics. Rheological parameters, that is, power law and IPC analysis with its physical characteristics were exploredat different storage temperatures (8°, 25°, 40° and 40° with 75% relative humidity- RH) with different time intervals up to 2 months of newly formulated poly-phenolic extract- based high internal phase cream and its comparison with base. Polyphenolic- based HIPCs showed non-Newtonian-pseudo plastic tendencies in vicissitudes with time and storage temperatures.
View Article and Find Full Text PDFOxf Med Case Reports
January 2021
Mycotic aneurysms of the carotid artery are a rare entity that can be fatal if not diagnosed promptly. We present a 60-year-old man with a tender left-sided neck mass due to a ruptured aneurysm of the left internal carotid artery. Cultures taken intraoperatively grew ser Dublin.
View Article and Find Full Text PDFNowadays, the use of wastewater for crop irrigation is increasing at global scale mainly due to freshwater scarcity and economic benefits. However, the presence of different types of pollutants including the trace elements (TEs) poses a serious threat to environmental and human health. This pot study evaluated the effect of alone and mixed irrigation water [wastewater (WW) with canal water (CW) and tube-well water (TW)] on TEs build-up in the soil, their soil-plant transfer and allied health hazards in District Vehari.
View Article and Find Full Text PDFAim of this study was to synthesize new inhibitors on the basis of active site of aspartic protease enzyme and to evaluate their intended biological activity. A3D model of an enzyme was generated via homology modeling and series of novel amide ligands were synthesized by using a short high yield process, subsequently, analyzed in-silico and in-vitro anti-leishmanial activities. Characterization and identification was accomplished via NMR (H& C), infrared and mass spectroscopic techniques.
View Article and Find Full Text PDFDiabetes occurs due to the excess of glucose in the blood that may affect many organs of the body. Elevated blood sugar in the body causes many problems including Diabetic Retinopathy (DR). DR occurs due to the mutilation of the blood vessels in the retina.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
January 2020
Background: Pain during painful procedures in neonates has far reaching consequences. In developed countries many non-pharmacological interventions are used for neonatal pain reduction. Breast feeding has been proved to be an effective analgesic during mild to moderate painful procedures in neonates.
View Article and Find Full Text PDFImmunotoxins are being investigated as anti-cancer therapies and consist of a cytotoxic enzyme fused to a cancer targeting antibody. All currently used toxins function via the inhibition of protein synthesis, making them highly potent in both healthy and transformed cells. This non-specific cell killing mechanism causes dose-limiting side effects that can severely limit the potential of immunotoxin therapy.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
April 2019
Background: Little is known about neonatal pain in Pakistan. So, to know about neonatal pain, its scoring and the effectiveness of oral dextrose in neonatal pain management we carried this study in neonatal intensive care unit (NICU) of military hospital (MH) Rawalpindi.
Methods: This randomized control trial was carried out in NICU of MH, Rawalpindi from Jan to Dec 2013.
MicroRNAs (also called miRNAs) are a group of short non-coding RNA molecules. They play a vital role in the gene expression of transcriptional and post-transcriptional processes. However, abnormality of their expression has been observed in cancer, heart diseases and nervous system disorders.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
November 2016
Background: Epidemiological data on thyroid cancer and associated risk factors are scarce in our setting. The present study was therefore designed to gather data which could be helpful in providing insights to thyroid physicians and surgeons for better management of affected patients.
Purpose: To determine the frequency of carcinoma thyroid among patients presenting with goiter and its association with TSH, Tg/ATg and other demographic factors.
Neonates with congenital malaria may present with non-specific signs and symptoms which may be mistaken for neonatal sepsis and inborn error of metabolism resulting in delay of diagnosis.and significant mortality and morbidity. Here we present a unique case of 25 days old premature female baby who was diagnosed to have mixed malarial infection.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
March 2015
Background: Loose motion is a common symptom in patients reporting to our hospital. As it is a small set up where only facility for microscopic stool examination is available, we designed this study to know how much microscopic stool examination can help us in management of patients with diarrhoea.
Methods: This cross-sectional descriptive study was conducted from January 2010 to April 2012, at Thall Scout Hospital, Hangoo, Khyber Pukhtoon Khwa, Pakistan.
Advance recycling through pyrolytic technology has the potential of being applied to the management of plastic waste (PW). For this purpose 1 l volume, energy efficient batch reactor was manufactured locally and tested for pyrolysis of waste plastic. The feedstock for reactor was 50 g waste polyethylene.
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