Publications by authors named "Sajede Saeidifard"

Article Synopsis
  • Progress in nanostructured self-assembling systems has led to the creation of various nanoscale shapes, but controlling structures across different lengths remains a challenge.
  • A new extrusion-based method was developed to produce aligned, nanofibrous hydrogels using self-assembling peptides, enhancing their strength when adjusting buffer concentrations during assembly.
  • These hydrogels can mimic extracellular matrices to guide cell behavior, but the relationship between matrix alignment and cell alignment is complex, highlighting the importance of understanding how cells interact with nanofibrous structures.
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Fibrous proteins that comprise the extracellular matrix (ECM) guide cellular growth and tissue organization. A lack of synthetic strategies able to generate aligned, ECM-mimetic biomaterials has hampered bottom-up tissue engineering of anisotropic tissues and led to a limited understanding of cell-matrix interactions. Here, we present a facile extrusion-based fabrication method to produce anisotropic, nanofibrous hydrogels using self-assembling peptides.

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Viruses have threatened animal and human lives since a long time ago all over the world. Some of these tiny particles have caused disastrous pandemics that killed a large number of people with subsequent economic downturns. In addition, the quarantine situation itself encounters the challenges like the deficiency in the online educational system, psychiatric problems and poor international relations.

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Considering the large consumption of nicotine and its sedative/stimulant effect on different organs of the body, the detection of low concentration of this material and its subsequent effect on live animals plays a significant role. Optical detection techniques such as plasmonics are the pioneers in highly sensitive detection techniques. However, for investigating the nicotine/smoke effect on live cells, not only the interaction between cell nicotine should be optimized but also the plasmonic interface should show a high sensitivity to the reception of nicotine by the cell receptors.

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