Synopsis of recent research by authors named "Saiyan Ji"
- Saiyan Ji’s recent research primarily focuses on the immunological aspects of various cancers, including colorectal cancer, glioma, and esophageal squamous cell carcinoma, employing advanced spatial proteomic technologies to elucidate tumor microenvironment characteristics and immune response dynamics
- Findings indicate that tumor-infiltrating lymphocytes (TILs), including CD3+ T cells, and immune marker expressions (like IDO1) serve as significant prognostic indicators for recurrence and metastasis in colorectal and esophageal cancers, respectively, emphasizing the role of immune profiling in cancer prognosis
- The studies also highlight the increased expression of STING in high-grade gliomas as associated with a high risk of recurrence, suggesting its potential as a therapeutic target, while novel histopathological markers were identified to stratify prognostic subgroups in colorectal adenocarcinoma effectively
