Computational Evaluation of Fusarium nygamai Compounds as AcrD Efflux Pump Protein Inhibitors of Salmonella Typhimurium.

In Salmonella Typhimurium, efflux pump proteins, such as AcrD actively expel drugs and hazardous chemicals from bacterial cells, resulting in treatment failure and the emergence of antibiotic-resistant variants. Focusing on AcrD may lead to the development of novel antimicrobials against multidrug-resistant bacteria. However, challenges persist in achieving high selectivity, low toxicity, and effective bacterial penetration.

Multistep Removal System of Gaseous Toluene: Adsorption, Electrochemical, and Photolytic Treatments.

A large amount of atmospheric emissions result from various anthropogenic activities worldwide. Given the complexity of volatile organic compounds (VOCs) and their different adsorption capacities, redox potentials, and photolytic properties, an air purification system for the removal of VOCs that combines multiple physical processes was proposed in this study using toluene as an example. These processes include, in the first step, an adsorption treatment (AT) with activated carbon (AC), where toluene adsorption results from the insertion of aromatic rings (nonpolar groups) between the graphitic carbon planes, as demonstrated by the Raman spectroscopy; in the second step, electrochemical treatment (ECT) using TiO|Ti||SS-304 electrodes applying an electric field to accelerate the oxidation of toluene through the production of free radicals (⋅OH), hydroperoxyl radicals and benzyl groups, followed by the rupture of aromatic rings to generate aliphatic compounds and the consequent mineralization to CO, CO, and HO; in the third step, photolytic treatment (PT) with a 254-nm UV lamp for toluene degradation is used, which is influenced by the addition of radicals, such as ⋅OH or ⋅O , to transform toluene into either benzene or phenol.

Treatment Challenges of Acquired Thrombotic Thrombocytopenic Purpura in Pediatric Patients From a Low-Income Country.

This study presents a comprehensive analysis of two cases of acquired thrombotic thrombocytopenic purpura (aTTP) observed in pediatric patients from a low-income country. In the instances described, both patients underwent a treatment regimen involving plasma exchange and immunosuppressive therapy conducted without the use of caplacizumab. Caplacizumab, an approved drug for adults known for its limited availability and high cost, has exhibited efficacy in reducing response time and recurrence frequency in aTTP cases.

Stem-cell transplantation for children with primary immune deficiencies: A retrospective study of 19 patients from one centre in Mexico.

Introduction: For many patients with primary immune deficiency (PID), stem-cell transplantation (SCT) may be life-saving.

Objective: To review our experience of 11 years transplanting children with PID in Mexico.

Methods: Chart review of patients who underwent SCT from 2008 to 2018, to describe their diagnoses, time to transplant, conditioning regime, survival rate and outcomes.

Studies of Charm Quark Diffusion inside Jets Using Pb-Pb and pp Collisions at sqrt[s_{NN}]=5.02 TeV.

The first study of charm quark diffusion with respect to the jet axis in heavy ion collisions is presented. The measurement is performed using jets with p_{T}^{jet}>60  GeV/c and D^{0} mesons with p_{T}^{D}>4  GeV/c in lead-lead (Pb-Pb) and proton-proton (pp) collisions at a nucleon-nucleon center-of-mass energy of sqrt[s_{NN}]=5.02  TeV, recorded by the CMS detector at the LHC.

Quantifying non-fibrous carbohydrates, acid detergent fiber and cellulose of forage through an in vitro gas production technique.

Background: The in vitro gas production (GP) technique has been useful for evaluating the potential degradability of feedstuffs in ruminal environments; GP is related to the components of feedstuff ingredients.

Results: Linear models were generated and validated as alternatives of quantifying neutral detergent-soluble fiber, starch (St)/hemicellulose (Hem) and cellulose (Cel) through GP. Residuals of models obtained from the peaks of GP [0-8 h (GP-8), > 8-24 h (GP-24), > 24-48 h (GP-48) and > 24-81 h (GP-81)] of 0.

Studies of Beauty Suppression via Nonprompt D^{0} Mesons in Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV.

The transverse momentum spectra of D^{0} mesons from b hadron decays are measured at midrapidity (|y|<1) in pp and Pb-Pb collisions at a nucleon-nucleon center of mass energy of 5.02 TeV with the CMS detector at the LHC. The D^{0} mesons from b hadron decays are distinguished from prompt D^{0} mesons by their decay topologies.

Sugar Concentration Measurement System Using Radiofrequency Sensor.

A sugar solution measurement system was developed based on the dielectric properties of the sucrose molecule. An ac conductivity and tan δ study as a function of the frequency was performed to find the suitable frequency range for the measuring system. The results indicate that it is possible to obtain a better response of the sensor using the frequencies as the maxima peak in tan δ appears.

Jet Shapes of Isolated Photon-Tagged Jets in Pb-Pb and pp Collisions at sqrt[s_{NN}]=5.02 TeV.

The modification of jet shapes in Pb-Pb collisions, relative to those in pp collisions, is studied for jets associated with an isolated photon. The data were collected with the CMS detector at the LHC at a nucleon-nucleon center-of-mass energy of 5.02 TeV.

Search for Dark Matter Particles Produced in Association with a Top Quark Pair at sqrt[s]=13 TeV.

A search is performed for dark matter particles produced in association with a top quark pair in proton-proton collisions at sqrt[s]=13  TeV. The data correspond to an integrated luminosity of 35.9  fb^{-1} recorded by the CMS detector at the LHC.

Measurement of associated production of a boson and a charm quark in proton-proton collisions at .

Measurements are presented of associated production of a boson and a charm quark ( ) in proton-proton collisions at a center-of-mass energy of 13 . The data correspond to an integrated luminosity of 35.7 collected by the CMS experiment at the CERN LHC.

Search for Narrow Hγ Resonances in Proton-Proton Collisions at sqrt[s]=13 TeV.

A search for heavy, narrow resonances decaying to a Higgs boson and a photon (Hγ) has been performed in proton-proton collision data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9  fb^{-1} collected with the CMS detector at the LHC in 2016. Events containing a photon and a Lorentz-boosted hadronically decaying Higgs boson reconstructed as a single, large-radius jet are considered, and the γ+jet invariant mass spectrum is analyzed for the presence of narrow resonances.

Author Correction: Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin.

The original version of this Article contained an error in the spelling of the authors J. H. Joly and N.

Synthesis of Ruthenium-Doped TiO₂ Nanotube Arrays for the Photocatalytic Degradation of Terasil Blue Dye.

The oxidation of terasil blue dye (TB) has been achieved by photocatalysis under UV light using well organized nanotubes of Ti/TiO₂ doped with ruthenium (Ru/Ti/TiO₂). Ru/Ti/TiO₂ were fabricated by Ti anodization followed by impregnation with 0.04, 0.

Search for the Higgs Boson Decaying to Two Muons in Proton-Proton Collisions at sqrt[s]=13 TeV.

A search for the Higgs boson decaying to two oppositely charged muons is presented using data recorded by the CMS experiment at the CERN LHC in 2016 at a center-of-mass energy sqrt[s]=13  TeV, corresponding to an integrated luminosity of 35.9  fb^{-1}. Data are found to be compatible with the predicted background.

Intelligent Spectroscopy System Used for Physicochemical Variables Estimation in Sugar Cane Soils.

The current condition of soils is a major area of interest due to the lack of certainty in their physicochemical properties, which can guarantee the quality and the production of a specific crop. Additionally, methodologies to improve land management must be implemented in order to address the consequences of many environmental issues. To date, many techniques have been implemented to improve the accuracy-and more recently the speed-of analysis, in order to obtain results while in the field.

Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin.

Although numerous therapeutic strategies have attempted to target aerobic glycolysis to inhibit tumor progression, these approaches have not resulted in effective clinical outcomes. Murine squamous cell carcinoma (SCC) can be initiated by hair follicle stem cells (HFSCs). HFSCs utilize aerobic glycolysis, and the activity of lactate dehydrogenase (Ldh) is essential for HFSC activation.

Observation of Medium-Induced Modifications of Jet Fragmentation in Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV Using Isolated Photon-Tagged Jets.

Measurements of fragmentation functions for jets associated with an isolated photon are presented for the first time in pp and Pb-Pb collisions. The analysis uses data collected with the CMS detector at the CERN LHC at a nucleon-nucleon center-of-mass energy of 5.02 TeV.

Search for Leptoquarks Coupled to Third-Generation Quarks in Proton-Proton Collisions at sqrt[s]=13 TeV.

Three of the most significant measured deviations from standard model predictions, the enhanced decay rate for B→D^{(*)}τν, hints of lepton universality violation in B→K^{(*)}ℓℓ decays, and the anomalous magnetic moment of the muon, can be explained by the existence of leptoquarks (LQs) with large couplings to third-generation quarks and masses at the TeV scale. The existence of these states can be probed at the LHC in high energy proton-proton collisions. A novel search is presented for pair production of LQs coupled to a top quark and a muon using data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.

Evidence for the Associated Production of a Single Top Quark and a Photon in Proton-Proton Collisions at sqrt[s]=13 TeV.

The first evidence of events consistent with the production of a single top quark in association with a photon is reported. The analysis is based on proton-proton collisions at sqrt[s]=13  TeV and recorded by the CMS experiment in 2016, corresponding to an integrated luminosity of 35.9  fb^{-1}.

Search for Pair-Produced Resonances Each Decaying into at Least Four Quarks in Proton-Proton Collisions at sqrt[s]=13 TeV.

This Letter presents the results of a search for pair-produced particles of masses above 100 GeV that each decay into at least four quarks. Using data collected by the CMS experiment at the LHC in 2015-2016, corresponding to an integrated luminosity of 38.2  fb^{-1}, reconstructed particles are clustered into two large jets of similar mass, each consistent with four-parton substructure.

Observation of the Z→ψℓ^{+}ℓ^{-} Decay in pp Collisions at sqrt[s]=13 TeV.

This Letter presents the observation of the rare Z boson decay Z→ψℓ^{+}ℓ^{-}. Here, ψ represents contributions from direct J/ψ and ψ(2S)→J/ψX, ℓ^{+}ℓ^{-} is a pair of electrons or muons, and the J/ψ meson is detected via its decay to μ^{+}μ^{-}. The sample of proton-proton collision data, collected by the CMS experiment at the LHC at a center-of-mass energy of 13 TeV, corresponds to an integrated luminosity of 35.

Observation of the χ_{b1}(3P) and χ_{b2}(3P) and Measurement of their Masses.

The χ_{b1}(3P) and χ_{b2}(3P) states are observed through their ϒ(3S)γ decays, using an event sample of proton-proton collisions collected by the CMS experiment at the CERN LHC. The data were collected at a center-of-mass energy of 13 TeV and correspond to an integrated luminosity of 80.0  fb^{-1}.

Elliptic Flow of Charm and Strange Hadrons in High-Multiplicity p+Pb Collisions at sqrt[s_{NN}]=8.16 TeV.

The elliptic azimuthal anisotropy coefficient (v_{2}) is measured for charm (D^{0}) and strange (K_{S}^{0}, Λ, Ξ^{-}, and Ω^{-}) hadrons, using a data sample of p+Pb collisions collected by the CMS experiment, at a nucleon-nucleon center-of-mass energy of sqrt[s_{NN}]=8.16  TeV. A significant positive v_{2} signal from long-range azimuthal correlations is observed for all particle species in high-multiplicity p+Pb collisions.