Elucidating early proton irradiation effects in metal halide perovskites via photoluminescence spectroscopy.

Metal halide perovskite (MHP) solar cells are promising aerospace power sources given their potential as inexpensive, lightweight, and resilient solar electricity generators. Herein, the intrinsic radiation tolerance of unencapsulated methylammonium lead iodide/chloride (CHNHPbICl) films was isolated. Spatially resolved photoluminescence (PL) spectroscopy and confocal microscopy revealed the fundamental defect physics through optical changes as films were irradiated with 4.

HO Mediated Photoreduction of Nitrates to Ammonia by Iron Filings under Ambient Conditions.

Herein, a simple ambient conditioned sunlight promoted photochemical reduction reaction is demonstrated for the of nitrate (NO) conversion to ammonia (NH) with the maximum conversion yield of ∼16 mM using iron filings (f-Fe) in the presence of HO. Based on a radical scavenging study of reactive species and the characterization of catalyst f-Fe before and after the reaction, a plausible mechanism has been proposed for the ambient conditioned synthesis of NH. The results associated with the NH synthesis have been verified using the N isotopic labeled nitrate (NO), which supports the simpler viability of the reported procedure.

Molecular Taxonomy Suggests Presence of Two Distinct Lineages of Blue Sheep (Pseudois nayaur) in Indian Himalayan Region.

Indian Himalayan Region (IHR) supports a plethora of biodiversity with a unique assemblage of many charismatic and endemic species. We assessed the genetic diversity, demographic history, and habitat suitability of blue sheep (Pseudois nayaur) in the IHR through the analysis of the mitochondrial DNA (mtDNA) control region (CR) and Cytochrome b gene, and 14 ecological predictor variables. We observed high genetic divergence and designated them into two genetic lineage groups, i.

Is ADDM graft practical? A comparative study to evaluate ADDM graft in third molar surgery.

Background: It has been outlined that LTM (Lower third molar) extracted from patients in which grinding, cleaning, sterilization & demineralization prove to be highly effective as graft material for filling the alveolar socket of the very same patient. These investigations aim to assess the efficiency of ADDM (Autogenous Demineralized Dentin Matrix) graft in third molar extraction sockets.

Purpose: To check the effectiveness of ADDM as graft material in extraction socket by evaluating pain, swelling, trismus, PD (Probing Depth) and bone density.

Molecular mechanisms of antiproliferative and pro-apoptotic effects of essential oil active constituents in MCF7 and T24 cancer cell lines: in vitro insights and in silico modelling of proapoptotic gene product-compound interactions.

This study aims to investigate the in vitro antiproliferative and pro-apoptotic/apoptotic potential of active constituents of essential oils on two cancer cell lines; namely, breast adenocarcinoma (MCF-7) and urinary bladder cancer (T24). Essential oils active constituents (EO-ACs) entail a spectrum of phytochemicals with widely demonstrated anticancer potential. We assessed the effects of eight essential oils active constituents on T24 and MCF-7 cell lines in both dose- (16-1024 µg/mL) and time-dependent manners.

An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase function.

MutT proteins are Nudix hydrolases characterized by the presence of a Nudix box, GX5EX7REUXEEXGU, where U is a bulky hydrophobic residue and X is any residue. Major MutT proteins hydrolyze 8-oxo-(d)GTP (8-oxo-GTP or 8-oxo-dGTP) to the corresponding 8-oxo-(d)GMP, preventing their incorporation into nucleic acids. Mycobacterial MutT1 comprises an N-terminal domain (NTD) harboring the Nudix box motif, and a C-terminal domain (CTD) harboring the RHG histidine phosphatase motif.

Investigating mechanical properties for developing a human infant cranial bone surrogate in pediatric craniofacial surgery.

Beyond the surgeon's feedback on bone behavior in the operating room, there is a paucity of data present in the literature on the mechanical properties of pediatric calvarial bone. The present study tested the calvarial bone of four species (Adult Humans, Dog, Pig, and Monkey) to find the mechanical properties. Three types of tests were performed; flexural, compression, and torsion to mimic how bone is handled during the surgery and the results were further compared with the existing published data for human pediatric calvarium.

Do different wheat ploidy levels respond differently against stripe rust infection: Interplay between reactive oxygen species (ROS) and the antioxidant defense system?

Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) is the most damaging wheat disease, causing substantial losses in global wheat production and productivity.

Structural and functional consequences of non-synonymous SNPs within the LAMA2 protein: a molecular dynamics perspective.

Clinical phenotypic presentations associated with LAMA2 deficiency have shown a variety of manifestations. LAMA2 mutations are mainly linked to congenital muscular dystrophy, but there is also mounting evidence suggesting their presence in inflammatory breast cancer, laryngopharyngeal squamous cell carcinoma, and ventricular tachycardia related to coronary artery disease and cardiomyopathy. This study examined the structural and functional impacts of 144 non-synonymous single nucleotide polymorphisms (nsSNPs) within the LAMA2 gene.

Understanding the Endocrine and Molecular Signaling Cascade Regulation Pathways in Children with Hypospadias.

Hypospadias (HS) is a congenital defect that occurs due to defective androgenization. It is characterized by the aberrant location of the urinary meatus on the ventral aspect of the penis with various degrees of severity. The molecular mechanisms and genetic associations underlying the condition remain largely unknown.

Prevalence of co-morbidities among periodontitis and non-periodontitis Indian patients.

Periodontitis being an immuno-inflammatory disease can act as an aggravating factor for various systemic diseases. Therefore, it is of interest to document the prevalence of comorbidities among periodontitis and non-periodontitis Indian patients. 680 patients were enrolled, categorized into non-periodontitis group (Group A) and periodontitis group (Group B).

Unveiling the role of the ERD15 gene in wheat's tolerance to combined drought and salinity stress: a meta-analysis of QTL and RNA-Seq data.

The coexistence of drought and salinity stresses in field conditions significantly hinders wheat (Triticum aestivum L.) productivity. Understanding the molecular mechanisms governing response and tolerance to these stresses is crucial for developing resilient wheat varieties.

Multistep Array-Based Sensing of Bioanalytes Using Modified MoS, Fluorescence Proteins, and Cucurbituril.

One pot sensor by multiplexing in the array is an attractive system for rapid discrimination of multiple analytes. Multiplexing can be achieved in two ways, i.e.

A conserved two-component system senses intracellular iron levels and regulates redox balance in spp.

For bacteria, an intricate coordination between sensing and regulating iron levels and managing oxidative stress is required as their levels are tightly interlinked. While various oxidative stress and heme-based redox sensors have been reported for both pathogenic and non-pathogenic bacteria, the mechanisms governing the modulation of intracellular iron levels in response to changes in redox status remain unclear. In this study, a gene-inactivated strain of mycobacterial sensor kinase PdtaS showed dysregulated expression of genes associated with iron metabolism, including Fe-S clusters, NADH dehydrogenases, and iron uptake.

CAR T-cell therapy in cancer: Integrating nursing perspectives for enhanced patient care.

Chimeric antigen receptor (CAR) T-cell therapy represents a significant advancement in cancer treatment, particularly for hematologic malignancies. Various cancer immunotherapy strategies are presently being explored, including cytokines, cancer vaccines, immune checkpoint inhibitors, immunomodulators monoclonal antibodies, etc. The therapy has shown impressive efficacy in treating conditions such as acute lymphoblastic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL), and multiple myeloma, often leading to complete remission in refractory cases.

Boosting cross-modal retrieval in remote sensing via a novel unified attention network.

With the rapid advent and abundance of remote sensing data in different modalities, cross-modal retrieval tasks have gained importance in the research community. Cross-modal retrieval belongs to the research paradigm in which the query is of one modality and the retrieved output is of the other modality. In this paper, the remote sensing (RS) data modalities considered are the earth observation optical data (aerial photos) and the corresponding hand-drawn sketches.

Flexible Organic Molecular Single Crystal-Based Triboelectric Device as a Self-Powered Tactile Sensor.

Triboelectric nanogenerators (TENGs) have proven to be effective at converting mechanical energy into electrical power, making them a viable technology for operating self-powered electronic devices used in medical diagnostics and environmental monitoring. In the present study, we demonstrate the utility of the flexible single crystals of an organic compound for the fabrication of a TENG as a self-powered tactile sensor. Triboelectrification was attained in single crystals as a result of surface functionalization with positively and negatively charged moieties, viz.

Room Temperature Single-Component Organic Multiferroics with Large Magnetoelectric Coupling: Proficient Approach for Stray-Magnetic Field Harvesting.

Magnetoelectric materials are highly desirable for technological applications due to their ability to produce electricity under a magnetic field. Among the various types of magnetoelectric materials studied, their organic counterparts provide an opportunity to develop solution-processable, flexible, lightweight, and wearable electronic devices. However, there is a rare choice of solution-processable, flexible, lightweight magnetoelectric materials which has tremendous technological interest.

Biotin-Pt(IV)-Ru(II)-Boron-Dipyrromethene Prodrug as "Platin Bullet" for Targeted Chemo- and Photodynamic Therapy.

Using the principle of "Magic Bullet", a cisplatin-derived platinum(IV) prodrug heterobimetallic complex, -[Pt(NH)Cl{Ru(tpy-BODIPY)(tpy-COO)}(biotin)]Cl (, ), having two axial ligands, namely, biotin as water-soluble B-vitamin for enhanced cellular uptake and a BODIPY-ruthenium(II) (, ) photosensitizer having ,,-donor tpy (4'-phenyl-2,2':6',2″-terpyridine) bonded to boron-dipyrromethene (BODIPY), is developed as a "Platin Bullet" for targeted photodynamic therapy (PDT). exhibited intense absorption near 500 nm and emission near 513 nm (λ = 488 nm) in a 10% dimethyl sulfoxide-Dulbecco's phosphate-buffered saline medium (pH 7.2).

Enhancing gait recognition by multimodal fusion of mobilenetv1 and xception features via PCA for OaA-SVM classification.

Gait recognition has become an increasingly promising area of research in the search for noninvasive and effective methods of person identification. Its potential applications in security systems and medical diagnosis make it an exciting field with wide-ranging implications. However, precisely recognizing and assessing gait patterns is difficult, particularly in changing situations or from multiple perspectives.

Optimal allocation of distributed energy resources to cater the stochastic E-vehicle loading and natural disruption in low voltage distribution grid.

The everyday extreme uncertainties become the new normal for our world. Critical infrastructures like electrical power grid and transportation systems are in dire need of adaptability to dynamic changes. Moreover, stringent policies and strategies towards zero carbon emission require the heavy influx of renewable energy sources (RES) and adoption of electric transportation systems.

Defining genomic landscape for identification of potential candidate resistance genes associated with major rice diseases through MetaQTL analysis.

Rice production is severely affected by various diseases such as bacterial leaf blight (BLB), brown spot (BS), false smut (FS), foot rot (FR), rice blast (RB), and sheath blight (SB). In recent years, several quantitative trait loci (QTLs) studies involving different populations have been carried out, resulting in the identification of hundreds of resistance QTLs for each disease. These QTLs can be integrated and analyzed using meta-QTL (MQTL) analysis for better understanding of the genetic architecture underlying multiple disease resistance (MDR).