Publications by authors named "Saina Dargahi"
Article Synopsis
- Thyroid hormones are crucial for brain development and can protect neurons from damage caused by methamphetamine.
- Researchers studied rat neurons and found that methamphetamine significantly reduces cell viability, but thyroid hormones T3 and T4 can prevent this damage.
- The protective effect of thyroid hormones involves activating specific cell surface receptors, suggesting new potential treatments for methamphetamine-related brain damage.
Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway.
Forouzan Azarafrouz Mohsen Farhangian Sara Chavoshinezhad Saina Dargahi Marjan Nassiri-Asl Leila Dargahi
Neuropeptides
October 2022
Interferon beta (IFNβ) is a cytokine with anti-apoptotic and anti-inflammatory properties, and its beneficial effects on Alzheimer's disease (AD) have been recently shown. The alterations in cerebral glucose uptake are closely linked to memory deficit and AD progression. The current study was designed to determine if IFNβ can improve recognition memory and brain glucose uptake in a rat model of AD.
View Article and Find Full Text PDF