Publications by authors named "Saime Sundus Uygun"

Objective: The objective of this study was to evaluate the efficacy and safety of isotonic and hypotonic intravenous fluids in maintenance fluid therapy for term infants.

Methods: This was a multi-centre, prospective, observational study conducted in 21 participating centres from December 30, 2020, to June 30, 2023. The study included term newborns requiring parenteral fluid therapy for maintenance (NCT04781361).

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Article Synopsis
  • - The study investigates the incidence of hypoxic ischemic encephalopathy (HIE) in infants ≥36 weeks gestational age in Turkey, finding an incidence rate of 2.13 per 1000 live births, with varying severity levels among those affected.
  • - Among infants with HIE, therapeutic hypothermia (TH) was notably administered to 34.5% of those with mild HIE, while factors like gestational age affected mortality rates, especially in those born at 34-35 weeks.
  • - Despite an unchanged incidence of HIE, the study revealed a decreased mortality rate and no significant impact of TH timing on MRI findings or mortality.
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  • The study investigates the clinical characteristics and outcomes of neonates with COVID-19 in Turkey, finding that symptomatic cases often experience respiratory issues.
  • Symptoms commonly included fever, hypoxemia, and cough, with a small percentage requiring mechanical ventilation.
  • High levels of C-reactive protein (CRP) and prothrombin time (PT) were associated with more severe cases, indicating a need for closer monitoring.
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Jeune syndrome (Asphyxiating thoracic dysplasia) is a rare dystrophy of the skeleton, inherited as an autosomal recessive condition. Patients develop a narrowed thorax, rhizomelic dwarfism, and hepatic, renal, and pancreatic abnormalities. High rates of pulmonary hypoplasia and pulmonary hypertension have been reported.

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Cystic echinococcosis, a zoonotic disease, is common in Turkey and is caused by the Echinococcus granulosus tapeworm. We describe the case of an 8-year-old girl who was admitted to hospital with chest wall asymmetry after a fall from height, without any other symptoms. Cystic lesion was identified on radiology, and serology supported the diagnosis of hydatid cyst.

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