Influence of Human Telomerase Reverse Transcriptase Mutation on the Aggressiveness and Recurrence in Meningiomas.

Background:  Over 200 human telomerase reverse transcriptase (hTERT) polymorphism combinations have been implicated in the development of cancer. This study aimed to evaluate hTERT mutations in meningioma tissue and its association with meningioma.

Material And Methods: A total of 90 patients who underwent surgery between 2006 and 2015 and were histopathologically diagnosed with meningioma (WHO 2016) were included.

Effects of prosthesis design and impression techniques on human cortical bone strain around oral implants under load.

Purpose: The purpose of this study was to evaluate the effects of two different prosthetic designs (screw-retained versus cement-retained) and two impression techniques (open versus closed tray) on bone-level strains around implants.

Materials And Methods: Two Ø 4.1 mm x 10 mm Straumann implants were placed in the bilateral fibulas of six fresh cadavers; bone segments were removed en bloc.

Morphologic, functional and behavioral effects of titanium dioxide exposure on nerves.

Objectives: The purpose of this study was to explore morphologic, functional, and behavioral effects of titanium dioxide (TiO(2)) on nerves.

Material And Methods: A total of 17 albino rats were used for nerve conduction experiments, hot-plate tests, and histological evaluation. TiO(2) was implanted unilaterally on the sciatic nerves of five rats.

Vascular response to titanium dioxide: a study on the rat carotid artery.

The purpose of this study was to explore the effects of titanium dioxide (TiO(2)) on vascular smooth muscle contractility with the use of the rat carotid-artery model. TiO(2) powder was implanted on right carotid arteries of five albino rats, the left arteries of which were left intact and served as controls. Fourteen days after placement, bilateral carotid arteries were removed and contraction/relaxation of isolated vessel rings were measured for dose-dependent epinephrine and acetylcholine administrations by a force displacement transducer.

Dynamic fatigue resistance of implant-abutment junction in an internally notched morse-taper oral implant: influence of abutment design.

Purpose: To compare dynamic fatigue resistance of one- and two-piece abutments connected to internally notched morse-taper oral implants.

Material And Methods: Sixteen synOcta ITI implants were tightened into two metal models. SynOcta abutments for cement-retained restorations and solid abutments were divided into two equal groups and were torque-tightened into the implants.

Mutagenic potentials of dental cements as detected by the Salmonella/microsome test.

The potential mutagenicity of a zinc phosphate (Poscal), a polycarboxylate (Aqualox) and glass ionomer cements with (Argion) and without (Meron) silver reinforcement were characterized by employing the Ames Salmonella/microsome test. The materials were eluted in dimethyl sulphoxide or physiologic saline and the aliquots were used either immediately or after an incubation period of 24h at 37 degrees C. Mutagenic effects of the materials were tested on Salmonella typhimurium strains TA 98, TA 100, TA 102 and TA 1535 using the standard plate incorporation assay, and in the presence or absence of S9 fraction from rat liver.

Cytotoxicity of eluates from a gamma-ray-polymerized poly(methyl methacrylate).

The purpose of this study was to evaluate the cytotoxicity of gamma-ray-polymerized poly(methyl methacrylate) (PMMA). A total of 32 disk-shaped PMMA specimens were polymerized by gamma-irradiation with 1 Mrad for 4 h (Group 1), 2 Mrad for 8 h (Group 2), 3 Mrad for 12 h (Group 3), and thermally polymerized (Group 4). Four- and 6-day eluates of the specimens were prepared in Eagle's Minimal Essential Medium (EMEM) without Fetal Calf Serum (FCS).

Role of mechanical environment and implant design on bone tissue differentiation: current knowledge and future contexts.

Objectives: To evaluate published evidence related to bone reactions to varying loading regimens and the impact of implant design on bone tissue differentiation.

Data And Sources: The literature was searched for original research articles relating effect of mechanical environment on bone tissue and effects of implant design on bone biomechanics and marginal bone reactions using MEDLINE and manual tracing of references cited in key papers otherwise not elicited.

Study Selection: Current literature on biomechanics of bone and dental implants as main focus and pertinent to key aspects of the review.

Effects of machined/turned, TiO2-blasted and sandblasted/acid-etched titanium oral implant surfaces on nerve conduction: a study on isolated rat sciatic nerves.

The purpose of this study was to explore the clinical relevance of the effects of machined/turned, TiO(2)-blasted and sandblasted/acid-etched titanium oral implant surfaces on nerve conduction. Isolated rat sciatic nerves were placed between two suction electrodes in a pyrex bath containing a tyrode solution. Evoked compound action potentials (cAPs) of the nerves were recorded before and after contact with the implants.

Biological reactions to a poly(L-lactide)-hydroxyapatite composite: a study in canine mandible.

In this study, bone response, possible use and ultimate fate of a chemically-synthesized poly(L-lactide)-hydroxyapatite (PLLA-HA) composite was experimented in canine mandible. Bilateral mandibular second premolars were extracted in four dogs. The PLLA-HA composite was placed into left surgical sites, and right extraction sites were used as controls.

Effects of hydroxyapatite-coated and commercially pure titanium oral implant surfaces on compound nerve action potentials.

The aim of this study was to investigate the effects of hydroxyapatite-coated and commercially pure titanium oral implants on nerve conduction. Isolated rat sciatic nerves were placed between two suction electrodes in a bath containing a tyrode solution. The implants were brought into intimate contact with the nerves and evoked compound action potentials (cAPs) were recorded before and after contact with the implants.

The influence of functional forces on the biomechanics of implant-supported prostheses--a review.

Objectives: To evaluate published evidence related to the influence of functional forces on the biomechanics of implant-supported prostheses.

Data And Sources: The literature was searched for original research articles relating control of loads on dental implants, effects of early and late occlusal loads, the influence of bone quality, prosthesis type, prosthesis material, number of supporting implants, and engineering techniques employed for evaluating mechanical and biomechanical behavior of implants using MEDLINE and manual tracing of references cited in key papers otherwise not elicited.

Study Selection: Current literature on implant biomechanics as main focus and pertinent to key aspects of the review.

A dual-purpose guide for optimum placement of dental implants.

Correct placement of implants is a requirement for implant treatment. The use of computed tomography and precise surgical guides is required when inadequate bone support is anticipated. This article describes the fabrication and use of an acrylic resin dual-purpose guide for radiographic evaluation of recipient sites and implant placement, which uses internally stacked stainless steel surgical guide channels.