Publications by authors named "Saili Moghe"

Article Synopsis
  • The gender of undergraduate research mentors plays a significant role in shaping students' research experiences in STEM fields, with female mentors positively impacting students' preparedness for scientific careers.
  • Research shows that while students typically do not choose mentors based on gender, those with female mentors rate their experiences more favorably.
  • Ensuring a balanced representation of female mentors in undergraduate research opportunities is crucial for maximizing the benefits of these experiences for all students.
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Article Synopsis
  • Cul3-RING ubiquitin ligases play a crucial role in various cellular processes, including controlling the cell cycle through the ubiquitylation of target substrates.* -
  • Depleting CUL3 and the BTB protein KLHL18 leads to delayed entry into mitosis due to inhibited activation of Aurora-A, a kinase essential for this process.* -
  • The study suggests that the CUL3-KLHL18 ligase is necessary for proper mitotic timing and coordinates the activation of Aurora-A at centrosomes.*
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Unperturbed mitosis is a prerequisite for the generation of two genetically identical daughter cells. Nucleolar-spindle associated protein (NuSAP) is an important mitotic regulator. The activity of NuSAP is essential for a variety of cellular events that occur during mitosis starting from spindle assembly to cytokinesis.

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