Publications by authors named "Saila Saarinen"
Article Synopsis
- Papillary thyroid cancer (PTC) is the most common type of thyroid cancer and can be inherited in families, prompting a study to find new genes and mechanisms linked to PTC susceptibility.
- Researchers focused on one family with PTC, using whole-genome sequencing, and also analyzed sporadic cases and familial adenomatous polyposis patients to search for genetic variants.
- They discovered specific gene variants in affected family members and found that the loss of the PDPR gene impacts glucose metabolism in thyroid cells, suggesting that PDPR might contribute to the risk of developing PTC.
