[Prognostic factors of antiangiogenic therapy response in neovascular macular degeneration].

Unlabelled: The apparent success of antiangiogenic therapy in patients with neovascular age-related macular degeneration (nAMD) shows the significance of effect prognosis and continuous observation.

Purpose: to study the influence of prognostic factors on the dynamics of functional and morphological response during anti-VEGF therapy in patients with nAMD.

Material And Methods: Retrospective analysis of anti-angiogenic therapy results was performed on the data of 1020 patients with nAMD.

[Certain aspects of the etiology of normal-pressure glaucoma].

Two groups of clinical-and-pathogenetic patients were defined through examining the hydrodynamics and hemodynamics of the eye in 67 patients (110 eyes) with normal pressure glaucoma (NPG); the below examinations methods were made use of: three-hour and one-day tonometry, tonography, determination of tolerance of the intraocular pressure (IOP), ultrasonic Doppler-graphy of the ocular artery and fluorescent angiography of the optic nerve. Tolerance of the original IOP, which was close to the age norm according to tonography readings, a reduced linear blood circulation, somewhat higher parameters of the peripheral resistance registered in the ocular artery (OA) and in the central retinal artery--(CRA)--(p < 0.05) and absolute defects of blood filling of the vascular system of the optic nerve disk (OND) were found to be typical of the group with a resistant and relatively low pressure (< or = 20 mm Hg), which was indicative of the predominant role of vascular disorders in the discussed patients.