Publications by authors named "Saif-Eddin Malhas"
Insulin resistance (IR), which can be assessed by triglyceride-glucose (TyG) index, is a major contributor to the pathogenesis of cardiovascular diseases. Arterial stiffness is an index of subclinical atherosclerosis. We conducted this systematic review and meta-analysis to summarize the existing studies and provide a quantitative assessment of the significance of the TyG index in predicting the incidence of subclinical atherosclerosis and arterial stiffness.
View Article and Find Full Text PDFInhaled pulmonary vasodilators (IPVD) have been previously studied in patients with non-coronavirus disease-19 (COVID-19) related acute respiratory distress syndrome (ARDS). The use of IPVD has been shown to improve the partial pressure of oxygen in arterial blood (PaO), reduce fraction of inspired oxygen (FiO) requirements, and ultimately increase PaO/FiO (P/F) ratios in ARDS patients. However, the role of IPVD in COVID-19 ARDS is still unclear.
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- * This systematic review analyzed 17 studies involving over 121,000 participants, finding that a higher TyG index is strongly linked to an increased risk of NAFLD, as shown by both pooled odds ratios (OR) and hazard ratios (HR).
- * The findings suggest that the TyG index could be a useful tool for identifying patients at high risk for NAFLD in clinical settings, prompting considerations for further testing and lifestyle modifications; however,
Systemic steroids are associated with reduced mortality in hypoxic patients with coronavirus disease 2019 (COVID-19). However, there is no consensus on the doses of steroid therapy in these patients. Several studies showed that pulse dose steroids (PDS) could reduce the progression of COVID-19 pneumonia.
View Article and Find Full Text PDFThe crystalloid fluid of choice in sepsis remains debatable. We aimed to perform a comprehensive meta-analysis to compare the effect of balanced crystalloids (BC) vs. normal saline (NS) in adults with sepsis.
View Article and Find Full Text PDFBackground: High-flow nasal cannula (HFNC) oxygen and noninvasive ventilation (NIV) have been widely used in patients with acute hypoxic respiratory failure (AHRF) due to COVID-19. However, the impact of HFNC versus NIV on clinical outcomes of COVID-19 is uncertain. Therefore, we performed this meta-analysis to evaluate the effect of HFNC versus NIV in COVID-19-related AHRF.
View Article and Find Full Text PDFIntroduction: Distal transradial artery access (DTRA) has recently gained attention due to potential benefits in terms of local complications. In this meta-analysis, we aimed to evaluate the utility of DTRA compared to conventional transradial artery access (CTRA) for coronary angiography and intervention.
Method: Multiple databases were searched from inception through May 2021 for all the studies that evaluated the efficacy and safety of DTRA in the coronary field.