Publications by authors named "Saif Aldeen Al-Ryalat"

Objective: The aim of this study is to evaluate the 100 most highly cited articles assessing posterior communicating artery aneurysms.

Methods: In May 2024, a comprehensive search was conducted in the Scopus database using the keyword "posterior communicating artery aneurysm" The top-100 most impactful articles were ranked by citation count and analyzed for relevant factors. Citations per year were calculated to minimize the risk of bias.

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With advancements in the implementation of artificial intelligence (AI) in different ophthalmology disciplines, it continues to have a significant impact on glaucoma diagnosis and screening. This article explores the distinct roles of AI in specialized ophthalmology clinics and general practice, highlighting the critical balance between sensitivity and specificity in diagnostic and screening models. Screening models prioritize sensitivity to detect potential glaucoma cases efficiently, while diagnostic models emphasize specificity to confirm disease with high accuracy.

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Article Synopsis
  • The study assesses the effectiveness of ChatGPT-4 in diagnosing glaucoma from color fundus photographs, using a benchmark dataset without prior training.
  • The results showed ChatGPT-4 achieved 90% accuracy in classifying images as either likely glaucomatous or not, though its sensitivity was lower at 50% and specificity high at 94.44%.
  • The findings suggest that advanced AI models like ChatGPT-4 could be beneficial in specialized medical fields, possibly requiring less training data and offering cost-effective solutions for diagnosis and healthcare support.
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Article Synopsis
  • - This study introduces a decision support system that utilizes machine learning to detect the severity of keratoconus, developed with input from both machine learning experts and ophthalmologists.
  • - By analyzing corneal measurements from Pentacam imaging, the researchers improved an imbalanced dataset and identified key features to build and validate three machine learning models, ultimately using the best-performing one in a web application.
  • - The system showed impressive metrics, including 98.62% accuracy, and is positioned for further evaluation by ophthalmologists for potential use as a clinical screening tool for keratoconus severity.
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Color vision deficiency (CVD) is an often-overlooked issue within the medical community, and its consequences remain insufficiently explored. We aim to evaluate how CVD affects diagnostic accuracy and distinguish between malignant choroidal melanoma and benign choroidal nevus among ophthalmologists. In this cross-sectional study, we engaged ophthalmologists through a web-based survey distributed via the professional ophthalmology society's social media channels.

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Hypertension is a prominent risk factor for cardiovascular and cerebrovascular diseases. Gender differences and menopausal status contribute to blood pressure changes across the lifespan which have not been completely characterized. Our study aims to explore the impact of multiple factors on blood pressure levels in previously healthy women and men.

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Background: The most accurate method of intraocular lens (IOL) power calculation in cataract surgery has not been determined, and further studies are needed to reach a consensus. The aim of this study was to assess publications related to IOL power calculation formulas, mapping their yearly trends, most productive authors, top publishing countries and institutions, and areas of specialization for IOL power formulas.

Methods: We conducted a comprehensive analysis of research articles published on the topic of IOL power calculation formulas.

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Article Synopsis
  • Post-transplant lymphoproliferative diseases (PTLD) are complex cancers that can occur after organ transplants, and research in this area has increased significantly over the past two decades.
  • A bibliometric analysis of PTLD publications from 2000 to 2022 revealed a total of 2,814 documents, with the United States producing the highest number of papers and citations, particularly from the University of Pittsburgh.
  • The study highlights key journals like Pediatric Transplantation and Transplantation, and provides insights for future research directions regarding PTLD.
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Purpose: Intrastromal corneal ring segment (ICRS) implantation is a surgical technique developed with the purpose of avoiding the progression of corneal protrusion and is considered a viable option for managing patients with keratoconus as it stabilizes or improves vision thus delaying or excluding the need of more advanced surgical intervention such as penetrating keratoplasty. However, long term follow up is still limited to determine its actual success in achieving this goal. The current project aims to provide an extended follow up reporting a mean followup of around 5 years, extending up to 12.

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Article Synopsis
  • The U.S. has made major progress in organ transplantation research over the past 50 years, reflected in increased academic output and the need for ongoing evaluations of the field.
  • A bibliometric analysis of transplantation journals revealed that the U.S. produced 25,956 research papers, which is 37.7% of global output, with Canada being the main collaborator.
  • Key institutions leading the research include the University of Pittsburgh and Mayo Clinic, with a focus on recipient outcomes and graft success, indicating a strong emphasis on improving patient results in transplantation.
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Objectives: Medical students have a lower quality of life (QoL) when compared to the general population. This lower QoL is associated with multiple factors such as burnout and depressive symptoms. QoL can be reflected in the degree of career satisfaction and career regret.

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Article Synopsis
  • Retinitis pigmentosa (RP) is often missed in early detection, and AI has shown potential as an effective diagnostic tool in identifying this condition using various eye imaging techniques.
  • A systematic review and meta-analysis were conducted on studies involving AI algorithms and ophthalmic images, evaluating their accuracy in diagnosing RP.
  • The results indicated that AI achieved high sensitivity (98.5%) and specificity (99.3%) in detecting RP, with a very high area under the curve (0.999), demonstrating excellent performance across the studies reviewed.
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In response to the COVID-19 pandemic, numerous initiatives have been implemented to ensure open access availability of COVID-19-related articles to make published articles accessible for anyone. This study aimed to assess the impact of the COVID-19 pandemic on open-access publishing in radiology and nuclear medicine. We conducted a comprehensive analysis of articles and reviews published in these fields during the COVID-19 publishing era using the Web of Science database.

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Introduction: ChatGPT (OpenAI, San Francisco, California, United States) is a chatbot powered by language-based artificial intelligence (AI). It generates text based on the information provided by users. It is currently being evaluated in medical research, publishing, and healthcare.

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There has been a recent surge in the number of publications centered on the use of artificial intelligence (AI) to diagnose various systemic diseases. The Food and Drug Administration has approved several algorithms for use in clinical practice. In ophthalmology, most advances in AI relate to diabetic retinopathy, which is a disease process with agreed upon diagnostic and classification criteria.

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Background: Robotic transplant surgery has garnered worldwide attention since 2002. Discussions on this issue have led to more publications over the past decade. This study assessed global robotic organ transplantation studies using bibliometric analysis.

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Objective: Keratoconus is a corneal ectasia that leads to thinning and steepening of the corneal surface. We aimed to assess the relationship between quality of life and corneal tomography indices, irrespective of visual acuity.

Methods: This was a cross-sectional study using a translated and validated Keratoconus Outcomes Research Questionnaire (KORQ) in Arabic language.

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Background: Color vision deficiency (CVD) is an under-reported problem among medical personnel, and its impact is still not well characterized. We aim to assess the impact of CVD among ophthalmologists on the accuracy of diagnosing different benign and malignant choroidal lesions.

Methods: This is a cross-sectional study conducted on ophthalmologists.

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Background: Abdominal solid organ transplant (SOT) programs have been hit hard by the COVID-19 pandemic, which was officially declared as such on March 11, 2020. Over two years, the tightening and softening of limitations in response to the "waves" of infection and COVID-19 fluctuations have provided distinct issues for waitlisted patients, transplant recipients, and transplant organizations.

Method: We searched Scopus using the terms "transplant" and "transplantation," and organ-related phrases like "intestin*," "liver," "kidney," "hepatic," "renal," and "pancrea*," as well as COVID-19 terms such as "COVID-19," "coronavirus," and "SARS-CoV-2.

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Background: Knee arthroscopy is a standard surgical procedure that is nowadays widely performed as day-case surgery. The aim of the study was to observe the effect of a single dose of intravenous corticosteroid on pain after undergoing knee arthroscopy for non-bony procedures.

Methods: A prospective, double-blind study design was adopted.

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Introduction: Several studies suggested a higher prevalence of hypertension and depression among medical students. Patients with depression have a higher prevalence of hypertension and vice versa. In this study, we assessed the frequency of hypertension and depression in a sample of medical students and the impact of depression on hypertension.

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Introduction: Hypertension is an important cause of morbidity and mortality worldwide. Undiagnosed hypertension is a serious issue that leads to increased morbidity and mortality. In this study, we aim to identify the prevalence of undiagnosed hypertension in the healthy Jordanian population, as well as identify predictors of high blood pressure readings in presumably healthy Jordanians.

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Purpose: This study aimed to assess preoperative predictors of visual outcome after phacoemulsification cataract surgery in Jordan, a Middle Eastern country.

Methods: This was a retrospective longitudinal study of adult patients who underwent phacoemulsification cataract surgery from January 2019 to July 2021. For each patient, we included only the first operated eye.

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Background: Sickle cell retinopathy (SCR) is one of the most important ocular manifestations of sickle cell disease (SCD). This study aims to assess the prevalence of SCR in SCD, identify risk factors for its development and progression to proliferative sickle cell retinopathy (PSCR), and evaluate the potential implications of these results on clinical practice.

Methods: This research is a secondary analysis of patients diagnosed with SCD from the epidemiological, multicenter Cooperative Study of Sickle Cell Disease (CSSCD).

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