Mesenchymal stem cells improve cardiac function in diabetic rats by reducing cardiac injury biomarkers and downregulating JAK/STAT/iNOS and iNOS/Apoptosis signaling pathways.

Cardiovascular complications are prevalent manifestations of type 2 diabetes mellitus (T2DM) and are usually the main cause of death. This study aims to show the underlying mechanisms of the potential therapeutic effect of mesenchymal stem cells (MSCs) on diabetic cardiac dysfunction. Twenty-four male Wistar rats were randomly assigned to one of three groups The control group received standard laboratory chow, and the groups with T2DM received a single dose of 45 mg/kg body weight of streptozotocin (STZ) after 3 weeks of pretreatment with a high-fat diet (HFD).

Retraction: Tracheal Bronchus: A Rare Etiology of Recurrent Pneumonia in Children.

[This retracts the article DOI: 10.7759/cureus.20378.

Tracheal Bronchus: A Rare Etiology of Recurrent Pneumonia in Children.

Recurrent infections are a common cause for seeking medical care and they result in significant parental anxiety and concerns. Although immunodeficiency disorders are an important underlying cause of recurrent infections, the majority of children with recurrent infections do not have any dysfunction in their immune systems. We present the case of an 11-year-old boy who was brought to the outpatient department by his parents because of a complaint of productive cough for the last one week that was associated with low-grade fever.