Scrotal Cooling to Protect Against Cisplatin-induced Spermatogenesis Toxicity: Preliminary Outcome of an Experimental Controlled Trial.

Objective: To investigate the protective effects of scrotal cooling on cisplatin-induced gonadal toxicity in an animal model.

Methods: Twenty-one male BALB/c mice were divided into 3 groups. The cisplatin group received 2 cycles of cisplatin (2.