Publications by authors named "Saida Khan"

Article Synopsis
  • Mozambique faces high rates of intimate partner violence (IPV) and mental health disorders, with significant gaps in treatment, prompting a study on implementing couple-based interpersonal therapy (IPT-C) in Nampula City.
  • Focus groups and interviews revealed stigma against mental health and norms around IPV as barriers, while stakeholders showed strong support for IPT-C despite resource limitations and suggested adaptations for addressing IPV.
  • Stakeholders advocated for community involvement, multilevel participation, and using technology to enhance resource availability for implementing IPT-C effectively in the community.
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Backgroud: Globally, women have been shown to have high rates of common mental disorders (CMDs). In low and middle-income countries (LMICs), women face significant challenges related to maternity. However, no study has compared mental health problems among pregnant/post-partum women, childless women of childbearing age, and women with children in a low-income country.

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Article Synopsis
  • Depression and anxiety disorders are prevalent in sub-Saharan Africa, particularly among individuals living with HIV (PWH).
  • A study compared the effectiveness of two brief screening tools, the Patient Health Questionnaire-4 (PHQ-4) and the Electronic Mental Wellness Tool-3 (E-mwTool-3), in diagnosing these disorders in healthcare settings in Maputo City, Mozambique.
  • Both tools showed strong sensitivity for detecting depression and anxiety in PWH, with E-mwTool-3 performing similarly to PHQ-4 for both HIV-positive and HIV-negative individuals.
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Background: The purpose of this study was to examine the impact of the COVID-19 pandemic on self-reported burnout of health workers, quality of care, and perceptions of COVID-19-related stigma in Mozambique.

Method: We conducted a cross-sectional quantitative assessment of 170 frontline health workers in Nampula District, Mozambique, including 149 (87.6%) primary care providers and 21 (12.

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Objective: Stepped mental health care requires a rapid method for nonspecialists to detect illness. This study aimed to develop and validate a brief instrument, the Mental Wellness Tool (mwTool), for identification and classification.

Methods: Cross-sectional development and validation samples included adults at six health facilities in Mozambique.

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The long-term effect of chronically implanted electrodes is the formation of a glial scar. Therefore, it is imperative to assess the biocompatibility of materials before employing them in neural electrode fabrication. Platinum alloy and iridium oxide have been identified as good candidates as neural electrode biomaterials due to their mechanical and electrical properties, however, effect of glial scar formation for these two materials is lacking.

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Neural electrode devices hold great promise to help people with the restoration of lost functions. However, research is lacking in the biomaterial design of a stable, long-term device. Glial scarring is initiated when a device is inserted into brain tissue and an inflammatory response ensues.

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This comprehensive literature review covers recent studies on patterning neuronal cells by topographical modifications on material surfaces targeted for neural prostheses. We explore different materials that are used as the candidate surface for neuronal cell adhesion. Cell-material interactions are identified in both cases where the material surface was in direct contact with cells and where the materials were coated to facilitate cell adhesion.

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Functional neural stimulation requires good interface between the neural cells and the electrode surfaces. In order to study the effect of electrode materials and surface structure on cell adhesion and biocompatibility, we cultured cortical neurons on thin films of platinum and iridium oxide. We used both flat, as-deposited and laser micro-structured films.

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The adherence and viability of neural cells (primary cortical cells) from rat embryo on silicon wafers with varying surface roughness (10 to 250 nm) at the nano scale were investigated. The roughnesses were achieved by using chemical etching. Atomic force microscopy was utilized to determine surface roughness.

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