Publications by authors named "Saida Hadi-Saljoqi"
Article Synopsis
- * The system provides scientific resources like databases, tools, and reference directories based on IMGT-ONTOLOGY to help researchers understand immune responses.
- * Research is organized into three main areas: identifying immunoglobulin and T cell receptor genes (Axis I), analyzing immune repertoires in various conditions (Axis II), and studying structural changes and engineering of antibodies and T cell receptors (Axis III).
IMGT®, the international ImMunoGeneTics information system® is the global reference in immunogenetics and immunoinformatics. By its creation in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS), IMGT® marked the advent of immunoinformatics, which emerged at the interface between immunogenetics and bioinformatics. IMGT® is specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility (MH), and proteins of the IgSF and MhSF superfamilies.
View Article and Find Full Text PDFIn teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During B cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique antigen receptor expressed on the surface of each lymphocyte. During the course of an immune response to infections or immunizations, B cell clones specific of epitopes from the immunogen are expanded and activated, leading to production of specific antibodies.
View Article and Find Full Text PDFIMGT(®), the international ImMunoGeneTics information system(®)(http://www.imgt.org) is the global reference in immunogenetics and immunoinformatics.
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