Electrospun zinc oxide nanoscaffolds: a targeted and selective anticancer approach.

This study aims to prepare, characterize, and evaluate zinc oxide nanoscaffolds (ZnO NSs) as a potential anticancer drug that selectively targets malignant cells while remaining non-toxic to normal cells. Electrospun NSs were fabricated and loaded with varying concentrations of ZnO nanoparticles (NPs). The uniform morphology of the fabricated samples was confirmed through Field Emission Scanning Electron Microscope (FESEM) imaging.

Development of 3-dimensionally printed denture base material utilizing hybrid polymer: A preliminary investigation.

Statement Of Problem: Current 3-dimensionally (3D) printed denture bases have inadequate strength and durability for long-term use, and milled denture bases generate excessive waste. Addressing these limitations is crucial to advancing prosthetic dentistry, ensuring improved patient outcomes and promoting environmental responsibility.

Purpose: The purpose of this in vitro study was to incorporate microparticles into a commercially available 3D printed denture base resin and compare its mechanical and biological properties with the conventional polymethyl methacrylate (PMMA) denture base material.

Assessment of enhancing curcumin's solubility versus uptake on its anti-cancer efficacy.

Curcumin (CUR) exhibits anti-inflammatory and anti-cancer activities. However, its poor solubility and bioavailability limit its therapeutic applications. Several CUR nano-formulations have been developed to enhance its solubility and uptake, thereby improving its anti-cancer activity.

Land in limbo: Nearly one third of Indonesia's cleared old-growth forests left idle.

Indonesia has experienced rapid primary forest loss, second only to Brazil in modern history. We examined the fates of Indonesian deforested areas, immediately after clearing and over time, to quantify deforestation drivers in Indonesia. Using time-series satellite data, we tracked degradation and clearing events in intact and degraded natural forests from 1991 to 2020, as well as land use trajectories after forest loss.

A review of the prospects, efficacy and sustainability of nanotechnology-based approaches for oil spill remediation.

Numerous marine oil spill incidents and their environmental catastrophe have raised the concern of the research community and environmental agencies on the topic of the offshore crude oil spill. The oil transport through oil tankers and pipelines has further aggravated the risk of the oil spill. This has led to the necessity to develop an effective, environment-friendly, versatile oil spill clean-up strategy.

Evaluation of urea breath test as a diagnostic tool for infection in adult dyspeptic patients.

In this editorial, we discuss the article in the . The article conducts a meta-analysis of the diagnostic accuracy of the urea breath test (UBT), a non-invasive method for detecting ( infection in humans. It is based on radionuclide-labeled urea.

The role of collagen triple helix repeat containing 1 (CTHRC1) in cancer development and progression.

Introduction: Collagen triple helix repeat containing 1 (CTHRC1) is a protein that has been implicated in pro-migratory pathways, arterial tissue-repair processes, and inhibition of collagen deposition via the regulation of multiple signaling cascades. Studies have also demonstrated an upregulation of CTHRC1 in multiple cancers where it has been linked to enhanced proliferation, invasion, and metastasis. However, the understanding of the exact role and mechanisms of CTHRC1 in cancer is far from complete.

Sustainable Power Generation Through Solar-Driven Integration of Brayton and Transcritical CO Cycles: A Comprehensive 3E (Energy, Exergy, and Exergoenvironmental) Evaluation.

Solar power tower technology has strong potential among the other concentration solar power techniques for large power generation. Therefore, it is necessary to make a new and efficient power conversion system for utilizing the solar power tower system. In present research, a novel combined cycle is proposed to generate power for the application of the solar power tower.

Anopheles mosquitoes in Morocco: implication for public health and underlined challenges for malaria re-establishment prevention under current and future climate conditions.

Background: The potential reappearance and/or expansion of vector-borne diseases is one of the terrifying issues awaiting humanity in the context of climate change. The presence of competent Anopheles vectors, as well as suitable environmental circumstances, may result in the re-emergence of autochthonous Malaria, after years of absence. In Morocco, international travel and migration movements from Malaria-endemic areas have recently increased the number of imported cases, raising awareness of Malaria's possible reintroduction.

Prevalence and associated factors of moderate to severe erectile dysfunction among adult men in Malaysia.

Erectile dysfunction (ED) is a pervasive problem among men, often shrouded in silence and stigma. This manuscript analysed the National Health and Morbidity Survey 2019 data to identify the prevalence of moderate to severe ED among men aged 18 and above in Malaysia and describe its associated factors. Self-administered questionnaire on ED utilised a locally validated International Index of Erectile Function.

Prevalence and sociodemographic predictors of high-risk vaginal human papillomavirus infection: findings from a public cervical cancer screening registry.

Introduction: High-risk human papillomavirus (HPV) screening is vital for early cervical cancer detection and treatment. With the introduction of the national cervical cancer screening programme and screening registry in Malaysia, there is a need to monitor population-based HPV screening uptake and high-risk HPV prevalence as part of cervical cancer surveillance.

Objective: To determine the prevalence and sociodemographic factors predicting high-risk HPV infection in Malaysia based on a public, community-based cervical cancer screening registry targeting women at risk of getting HPV infection.

Polymer-Based Hydrogel Loaded with Honey in Drug Delivery System for Wound Healing Applications.

Excellent wound dressings should have crucial components, including high porosity, non-toxicity, high water absorption, and the ability to retain a humid environment in the wound area and facilitate wound healing. Unfortunately, current wound dressings hamper the healing process, with poor antibacterial, anti-inflammatory, and antioxidant activity, frequent dressing changes, low biodegradability, and poor mechanical properties. Hydrogels are crosslinked polymer chains with three-dimensional (3D) networks that have been applicable as wound dressings.

A Comparison of the National Cervical Cancer Policies in Six Developing Countries with the World Health Organization Recommendations: A Narrative Review.

Background: This study reviewed cervical cancer policies implemented in developing countries that adhered to WHO standards. Despite long being known as a preventable disease, cervical cancer is still one of the leading causes of mortality among women. Nine out of ten cervical cancer deaths occurred in less-developed countries, suggesting that the preventive and control approaches in these countries might differ from those in developed nations.

Anti-SARS-CoV-2 potential of castor oil plant () leaf extract: virtual evidence.

L. is a medicinal plant that displays valuable pharmacological properties, including antioxidant, antimicrobial, analgesic, antibacterial, antiviral and anti-inflammatory properties. This study targeted to isolate and identify some constituents of leaves using ultra-performance liquid chromatography coupled with mass spectroscopy (UPLC-MS/MS) and different chromatographic techniques.

Description of Poly(aryl-ether-ketone) Materials (PAEKs), Polyetheretherketone (PEEK) and Polyetherketoneketone (PEKK) for Application as a Dental Material: A Materials Science Review.

Poly(aryl-ether-ketone) materials (PAEKs), a class of high-performance polymers comprised of polyetheretherketone (PEEK) and polyetherketoneketone (PEKK), have attracted interest in standard dental procedures due to their inherent characteristics in terms of mechanical and biological properties. Polyetheretherketone (PEEK) is a restorative dental material widely used for prosthetic frameworks due to its superior physical, mechanical, aesthetic, and handling features. Meanwhile, polyetherketoneketone (PEKK) is a semi-crystalline thermoplastic embraced in the additive manufacturing market.

Spectral Fingerprint of Quantum Confinement in Single CsPbBr Nanocrystals.

Lead halide perovskite nanocrystals are promising materials for classical and quantum light emission. To understand these outstanding properties, a thorough analysis of the band-edge exciton emission is needed, which is not reachable in ensemble and room-temperature studies because of broadening effects. Here, we report on a cryogenic-temperature study of the photoluminescence of single CsPbBr nanocrystals in the intermediate quantum confinement regime.

Effect of Different Vat Polymerization Techniques on Mechanical and Biological Properties of 3D-Printed Denture Base.

Three-dimensional printing is increasingly applied in dentistry to fabricate denture bases. Several 3D-printing technologies and materials are available to fabricate denture bases, but there is data scarcity on the effect of printability, mechanical, and biological properties of the 3D-printed denture base upon fabricating with different vat polymerization techniques. In this study, the NextDent denture base resin was printed with the stereolithography (SLA), digital light processing (DLP), and light-crystal display (LCD) technique and underwent the same post-processing procedure.

The Impact of Cavities in Different Thermal Applications of Nanofluids: A Review.

Nanofluids and nanotechnology are very important in enhancing heat transfer due to the thermal conductivity of their nanoparticles, which play a vital role in heat transfer applications. Researchers have used cavities filled with nanofluids for two decades to increase the heat-transfer rate. This review also highlights a variety of theoretical and experimentally measured cavities by exploring the following parameters: the significance of cavities in nanofluids, the effects of nanoparticle concentration and nanoparticle material, the influence of the inclination angle of cavities, heater and cooler effects, and magnetic field effects in cavities.

Intelligent approaches for sustainable management and valorisation of food waste.

Food waste (FW) is a severe environmental and social concern that today's civilization is facing. Therefore, it is necessary to have an efficient and sustainable solution for managing FW bioprocessing. Emerging technologies like the Internet of Things (IoT), Artificial Intelligence (AI), and Machine Learning (ML) are critical to achieving this, in which IoT sensors' data is analyzed using AI and ML techniques, enabling real-time decision-making and process optimization.

Fables of scarcity in IP.

In this chapter, I use methods drawn from literary analysis to bear on artificial scarcity and explore how literary and legal storytelling engages in scarcity mongering. I find three particular narrative strategies calculated to compel a conclusion in favor of propertization: the spectacle of need, the diversionary tactic, and the rallying cry. First, I unpack the spectacle of need and its diversionary aspects through several literary accounts of scarcity and starvation.

COVID-19-induced transaminitis and hyperbilirubinemia: Presentation and outcomes.

The risk of liver injury in patients with coronavirus disease 2019 (COVID-19) infection is quite evident. Furthermore, liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of vaccines. This editorial describes liver involvement during COVID-19 infection in patients with or without preexisting liver injury, such as chronic liver disease, to elucidate COVID-19-induced liver function abnormalities and their severity, pathophysiology, clinical manifestations, and clinical and laboratory outcomes.

Energy saving potential analysis applying factory scale energy audit A case study of food production.

An energy audit (EA) is a crucial step in boosting factory energy efficiency and obtaining certification for cleaner manufacturing. The results of a preliminary energy audit carried out at a sizable industrial facility in Jordan that creates some of the most well-known foods in the Middle East are presented in this study. The monthly demand of the factory for diesel ranged from 75,251.

Radical reform of the undergraduate medical education program in a developing country: the Egyptian experience.

Medical educators are in a continuous quest to close the gap between the needs of medical practice and the rising expectations of the communities in their countries. During the past two decades, competency-based medical education has been evolving as an appealing strategy to close this gap. In 2017, the Egyptian medical education authorities mandated all medical schools to change their curricula to comply with revised national academic reference standards, which changed from outcome-based to competency-based.

Axotomy results in an increase in Thy-1 protein in the 35-day-old rat supraoptic nucleus.

We demonstrated previously that the hypothalamic supraoptic nucleus (SON) undergoes an axonal sprouting response following a unilateral lesion of the hypothalamo-neurohypophysial tract in a 35-day-old rat to repopulate the partially denervated neural lobe (NL). However, no sprouting occurs following the same injury in a 125-day-old rat. We previously reported a significant increase in Thy-1 protein in the SON of a 125-day-old rat compared to a 35-day-old rat in the absence of injury.