Background: The activation of complement during platelet activation is incompletely understood.
Objectives: We sought to explore the formation of C5b-9 and anaphylatoxins binding to collagen-activated platelets.
Methods: C5b-9, anaphylatoxins C3a, C4a and C5a, and anaphylatoxin receptors C3aR1 and C5aR were measured by flow cytometry and/or confocal microscopy.