Publications by authors named "Sai-di Jin"
Article Synopsis
- Cardiac fibrosis is a harmful process leading to heart failure, and this study focuses on a specific circular RNA called circNSD1 and its relationship with the miRNA miR-429-3p in regulating this condition.
- Researchers created mouse models of heart attack (myocardial infarction) and studied heart cells to observe that miR-429-3p is decreased in cardiac fibrosis, leading to the conclusion that it helps prevent this condition.
- The study shows that circNSD1 acts as a sponge for miR-429-3p, and reducing circNSD1 may reduce cardiac fibrosis, suggesting circNSD1 could be a new target for treating heart-related diseases.
The present study was aimed to investigate the effects of circRNA-0028171 on the apoptosis of vascular endothelial cells induced by arsenic trioxide (AsO). Human umbilical vein endothelial cells (HUVECs) were treated with 0-15 μmol/L AsO for 24 h. Then, cellular viability was measured by MTT assay.
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