Publications by authors named "Sai-Lun Lee"
Article Synopsis
- Anthrax protective antigen (PA) stops blood vessel growth in a way we don’t fully understand yet.
- It's been found that a protein called CMG2 is really important for this stopping action, while another protein called TEM8 is not as critical.
- Targeting CMG2 could be a new method to prevent unwanted blood vessel growth, which is helpful in some diseases.
Capillary Morphogenesis Gene 2 protein (CMG2) is a transmembrane, integrin-like receptor and the primary receptor for the anthrax toxin. CMG2 also plays a role in angiogenic processes. However, the molecular mechanism that mediates the observed CMG2-related angiogenic effects is not fully elucidated.
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