Cocaine use disorder (CUD) is a serious condition characterized by an uncontrollable desire to use cocaine, even with negative consequences, and is linked to abnormalities in brain connectivity based on MRI studies.
This research compared brain networks in CUD patients and healthy controls, incorporating both structural and functional connectivity using advanced imaging techniques, involving 63 CUD patients and 42 healthy participants.
The findings indicated that traditional methods might miss important connections; multimodal analysis revealed deeper insights into brain region interactions affected by cocaine use and could inform improved treatment strategies.