Cryopreserved Thyroid Tissue Autotransplant in Pediatric Age Patients: A Feasibility Study and Literature Review.

Background And Aims: This paper aims to study an alternative solution to hormonal replacement therapy in specific groups of patients who underwent thyroidectomy during childhood or adulthood. After cryopreservation, thyroid autotransplantation could be an alternative solution which would allow us to use the ability of the thyroid tissue of producing hormones according to the physiological needs of the body.

Materials And Methods: A feasibility study about the effects of the most modern cryopreservation techniques on the structural and functional integrity of the follicular cells of the thyroid tissue has been carried out.

Real-World Data Assessing the Impact of Lymphovascular Space Invasion on the Diagnostic Performance of Sentinel Lymph Node Mapping in Endometrial Cancer.

Background: SLN mapping has emerged as a standard of care in endometrial cancer due to its high sensitivity and significant reduction in morbidity. Although lymphovascular space invasion (LVSI) is a known risk factor for lymph node metastasis and recurrence, evidence on the reliability of SLN mapping in LVSI-positive patients is scarce. The aim of this study was to determine the impact of LVSI on the diagnostic performance of SLN mapping.

DICER1 Syndrome: A Multicenter Surgical Experience and Systematic Review.

DICER1 syndrome is a rare genetic disorder that predisposes patients to the development of malignant and non-malignant diseases. Presently, DICER1 syndrome diagnosis still occurs late, usually following surgical operations, affecting patients' outcomes, especially for further neoplasms, which are entailed in this syndrome. For this reason, herein we present a multicenter report of DICER1 syndrome, with the prospective aim of enhancing post-surgical surveillance.

Arabic validation of a cyberbullying assessment instrument.

Introduction: Cyberbullying is a new form of peer violence that has become a widespread problem in the world. The prevalence of this phenomenon is not known in Tunisia due to the absence of validated assessment instruments. The aim of this study was to translate and validate the questionnaire "Second Revision of the Revised Cyberbullying Inventory".

NRS-2002 components, nutritional score and severity of disease score, and their association with hospital length of stay and mortality.

Background: Malnutrition is a substantial issue in hospitals, leading to prolonged length of hospital stay, increased perioperative morbidity and increased mortality. There are several validated screening tools for malnutrition, one of which is the Nutritional Risk Screening 2002 (NRS). It screens patients based on recent weight loss, reduction of recent food intake, body mass index (BMI), severity of disease and age.

[Place of the respiratory physiotherapist in the Covid-19 crisis: Neuchâtel experience].

The physiotherapy service became an important player in the care of patients with COVID-19 at Pourtalès hospital (Neuchâtel, Switzerland), illustrating its important role in the organization of acute care units. The workforce was increased, and the diaries extended (7/7d, 24/24h). Respiratory physiotherapists were largely involved in the initiation and the adaptation of the respiratory therapy in the units dedicated to Covid-19 patients (emergency, intensive care and pulmonology units), such as oxygen therapy and both invasive and non-invasive ventilation.

New exploration of the γ-gliadin structure through its partial hydrolysis.

The partial enzymatic hydrolysis of wheat gliadins constitutes an interesting tool to unravel their structural specificity. In this work, the structure and conformation of γ-gliadin were investigated through its limited chymotrypsic digestion. Using a combination of computational, biochemical and biophysical tools, we studied each of its N and C terminal domains.

Ultrasound Based Planning and Navigation for Non-Anatomical Liver Resections - An Study.

Non-anatomical resections of liver tumors can be very challenging as the surgeon cannot use anatomical landmarks on the liver surface or in the ultrasound image for guidance. This makes it difficult to achieve negative resection margins (R0) and still preserve as much healthy liver tissue as possible. Even though image-guided surgery systems have been introduced to overcome this challenge, they are still rarely used due to their inaccuracy, time-effort and complexity in usage and setup.

Role of protein conformation and weak interactions on γ-gliadin liquid-liquid phase separation.

Wheat storage proteins, gliadins, were found to form in vitro condensates in 55% ethanol/water mixture by decreasing temperature. The possible role of this liquid-liquid phase separation (LLPS) process on the in vivo gliadins storage is elusive and remains to be explored. Here we use γ-gliadin as a model of wheat proteins to probe gliadins behavior in conditions near physiological conditions.

Angiotensin-converting enzyme insertion/deletion gene polymorphisms and the risk of glioma in an Algerian population.

Introduction: Just recently, it has been established that the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism is linked to the pathogenesis and to the evolution of human cancers. Therefore, the present study was concerned with the investigation of an eventual association between glioma and I/D polymorphism of the ACE gene.

Methods: The expression of ACE gene was detected by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis in 36 Algerian patients with glioma and 195 healthy controls.

Using tree leaves and barks collected from contaminated and uncontaminated areas as indicators of air metallic pollution.

The aim of this study was to show the usefulness of woody species in assessing air pollution by cadmium, copper, lead, and zinc. For this, washed leaves, unwashed leaves, and barks of a coniferous species ( var. ) and a broadleaved one ( F.

Positive predictive values of selected hospital discharge diagnoses to identify infections responsible for hospitalization in the French national hospital database.

Purpose: The identification of infections in electronic health databases is a key issue for pharmacoepidemiology research. The aim of this study was to assess the positive predictive values (PPVs) of hospitalizations for infection in the Système National d'Information Inter-régimes de l'Assurance Maladie, that is the electronic database recording in-and-out hospital data for the entire French population (66 million inhabitants).

Methods: The source of data was the database of hospitalizations (Programme de Médicalisation des Systèmes d'Informations) of Toulouse University hospital, South of France (2880 beds).

Spatial and seasonal variations and ecotoxicological significance of sediment trace metal concentrations in Kebir-Rhumel basin (Northeast of Algeria).

This study sought to assess sediment contamination by trace metals (cadmium, chromium, cobalt, copper, manganese, nickel, lead and zinc), to localize contaminated sites and to identify environmental risk for aquatic organisms in Wadis of Kebir Rhumel basin in the Northeast of Algeria. Water and surficial sediments (0-5 cm) were sampled in winter, spring, summer and autumn from 37 sites along permanent Wadis of the Kebir Rhumel basin. Sediment trace metal contents were measured by Flame Atomic Absorption Spectroscopy.

Assessment of sediment quality and pore water ecotoxicity in Kebir Rhumel basin (NE-Algeria): a combined approach.

The objectives of this study are to use different approaches to assess the current pollution status in the wadis of the Kebir Rhumel basin. First, sediment trace metal contents were measured by flame atomic absorption spectroscopy. Then, sediment quality was assessed on the basis of contamination assessment indexes such as: Geoaccumulation Index (Igeo), Contamination factor (C(f)), Contamination degree (C(d)), Sediment Pollution Index (SPI) and SEQ guidelines (Consensus Sediment Quality Guidelines).

New methodological improvements in the Microtox® solid phase assay.

The classic Microtox® solid phase assay (MSPA) based on the inhibition of light production of the marine bacteria recently renamed Aliivibrio fischeri suffers from various bias and interferences, mainly due to physico-chemical characteristics of the tested solid phase. To precisely assess ecotoxicity of sediments, we have developed an alternative method, named Microtox® leachate phase assay (MLPA), in order to measure the action of dissolved pollutants in the aqueous phase. Two hypotheses were formulated to explain the observed difference between MSPA and MLPA results: a real ecotoxicity of the solid phase or the fixation of bacteria to fine particles and/or organic matter.