Publications by authors named "Sahini Gajula"
Background Advances in cancer treatment have markedly improved survival rates but have also heightened morbidity due to treatment-related side effects. Despite this, the literature remains scarce on predicting the incidence of acute cardiac toxicity resulting from chemotherapy. We conducted a prospective evaluation to assess the incidence, timing, clinical correlates, global longitudinal strain (GLS), and response to heart failure (HF) therapy in patients experiencing cardiotoxicity.
View Article and Find Full Text PDFLeft ventricular non-compaction cardiomyopathy, often known as LVNC, is a form of congenital cardiomyopathy that is extremely uncommon. It is a condition that may be identified by an elevated number of endomyocardial trabeculations as well as an increase in their prominence. Alcoholic cardiomyopathy, also known as ACM, is a non-ischemic form of dilated cardiomyopathy that is characterized by contractile failure and an enlargement of the heart ventricles.
View Article and Find Full Text PDFArticle Synopsis
- Harlequin ichthyosis (HI) is a rare and severe genetic disorder caused by mutations in the ABCA12 gene, leading to abnormal skin development characterized by thick, diamond-shaped plates of keratinized skin.
- Affected infants typically show symptoms at birth, including tight skin, deep cracks, and increased risks for complications like breathing and feeding challenges, infections, dehydration, and temperature issues.
- While HI has a high mortality rate, especially in newborns, early detection and better understanding of the condition can improve management and quality of life for those affected.