Characterizing the electrical activity of cardiomyocytes and neurons is crucial in understanding the complex processes in the heart and brain tissues, both in healthy and diseased states. Micro- and nanotechnologies have significantly improved the electrophysiological investigation of cellular networks. Carbon-based nanomaterials or nanocarbons, such as carbon nanotubes (CNTs), nanodiamonds (NDs) and graphene are promising building blocks for bioelectronics platforms owing to their outstanding chemical and physical properties.
View Article and Find Full Text PDFIntroduction: Cell-cell communication plays a pivotal role in biological systems' coordination and function. Electrical properties have been linked to specification and differentiation of stem cells into targeted progeny, such as neurons and cardiomyocytes. Currently, there is a critical need in developing new ways to complement fluorescent indicators, such as Ca-sensitive dyes, for direct electrophysiological measurements of cells and tissue.
View Article and Find Full Text PDFFor more than a century, blood agar plates have been the only test for beta-hemolysis. Although blood agar cultures are highly predictive for bacterial pathogens, they are too slow to yield actionable information. Here, we show that beta-hemolytic pathogens are able to lyse and release fluorophores encapsulated in sterically stabilized liposomes whereas alpha and gamma-hemolytic bacteria have no effect.
View Article and Find Full Text PDFIn recent years graphene has drawn considerable research interest for biomedical applications. However, applications of graphene in biological systems also raise concerns about its possible toxicity. Here, by using live cell imaging techniques, we investigate the effect of pristine graphene on the viability as well as stress of both nonneuronal and neuronal cells under physiological conditions.
View Article and Find Full Text PDFIn recent years, there has been a growing interest in using graphene as a synthesis platform for polymers, zero-dimensional (0D) materials, one-dimensional materials (1D), and two-dimensional (2D) materials. Here, we report the investigation of the growth of germanium nanowires (GeNWs) and germanium nanocrawlers (GeNCs) on single-layer graphene surfaces. GeNWs and GeNCs are synthesized on graphene films by gold nanoparticles catalyzed vapor-liquid-solid growth mechanism.
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