Serum Apo Lipoprotein E, Apo Lipoprotein E Gene Polymorphisms, and Parkinson's Disease.

Background: A central role for apolipoprotein E (APOE) has been suggested in modulating processes of neurodegeneration.

Objective: To study the association between serum APOE levels, APOE gene polymorphisms, and Parkinson's disease (PD).

Material And Methods: Fifty-five patients with PD and 30 healthy subjects were enrolled.

Evaluation of Branched-Chain Amino Acids in Children with Autism Spectrum Disorder and Epilepsy.

Autism spectrum disorder (ASD) and epilepsy run hand-to-hand in their pathophysiology. Epilepsy is not an uncommon finding in patients with ASD. The aim of the present study was to identify the metabolic abnormalities of BCAAs (leucine, isoleucine, and valine) in children with ASD with and without seizures in comparison with neurotypical controls.

Altered S100 Calcium-Binding Protein B and Matrix Metallopeptidase 9 as Biomarkers of Mesial Temporal Lobe Epilepsy with Hippocampus Sclerosis.

Mesial temporal lobe epilepsy (MTLE) associated with hippocampal sclerosis (HS) is the most common form of partial epilepsy. The aim of the present study is to highlight possible and suitable biomarkers that can help in the diagnosis and prognosis of this intractable form of epilepsy. The study was carried out on 30 epileptic patients of both sexes with complex partial seizures, having an age ranging from 4 to 30 years and were selected from the outpatient epilepsy clinic at the Kasr El-Aini Hospital in Cairo, Egypt.

Predictors of stroke outcome: the role of hemorheology, natural anticoagulants, and serum albumin.

Background: The early hours after an acute stroke are crucial; early accurate prediction of outcome in stroke patients can help health system providers and families to choose appropriate lines of management and plan for the future. The aim of this work is to assess the role of hemorheological parameters (such as blood viscosity, hematocrit, platelet aggregation, and leukocyte count), protein C, protein S, antithrombin III, and serum albumin as predictors of stroke outcome.

Methods: Thirty subjects, 20 patients with acute ischemic stroke within 24 h from the onset and 10 normal subjects, were included in this case control study.

Epilepsy prevalence in Al-Manial Island, Egypt. A door-to-door survey.

Background: Epidemiologic studies of epilepsy are lacking from the majority of the Arab countries; although there are significant needs for such studies. This study was conducted on a sample of Al-Manial Island, Cairo city, one of the highest cities in population density in the world.

Participants And Methods: A community-based, door to door, cross-sectional study using multistage random sample including 512 families (1751 individuals).