Publications by authors named "Sahar Khastar"
Long Non-Coding RNAs in Non-Alcoholic Fatty Liver Disease; Friends or Foes?
Cell Biochem Biophys
October 2024
Article Synopsis
- Metabolic dysfunction-associated fatty liver disease (MAFLD) involves fat accumulation in the liver and can progress to severe stages like steatohepatitis and fibrosis, influenced by both environmental and genetic factors.
- Long non-coding RNAs (lncRNAs) are RNA molecules that regulate gene expression and have been linked to various liver diseases, including MAFLD, although their specific roles in this condition remain largely unclear.
- This review highlights recent findings on lncRNAs in MAFLD's development and explores their potential as therapeutic targets for managing this prevalent liver disease.
Although the number of breast cancer deaths has decreased, and there have been developments in targeted therapies and combination treatments for the management of metastatic illness, metastatic breast cancer is still the second most common cause of cancer-related deaths in U.S. women.
View Article and Find Full Text PDFBackground: The use of dental pulp stem cells (DPSCs) in clinical applications instead of bone marrow stem cells is a very promising method capable of significantly changing the future of medical treatment. If further studies prove that DPSCs and the cells differentiated from them do not stimulate the immune system, these cells can be used more reliably in treatment of autoimmune diseases.
Methods: In this research, we examined the isolated DPSCs and differentiated osteoblasts from them in medium without inflammatory stimulants in terms of TLR3 and TLR4 gene expression and inflammatory cytokines, including TNF-α and IL-8 using qRT-PCR, and measured the concentration of inflammatory cytokines IL-8 and TNF-α produced by these two types of cells through ELISA.