Publications by authors named "Sahar Isa AlThawadi"

Introduction: In December 2019, a new severe acute respiratory syndrome coronavirus, SARS-CoV-2, emerged in China, causing coronavirus disease 2019. The present study investigated genetic profiles and variations of SARS-CoV-2 distributed in different regions of Saudi Arabia to begin to understand the pathogenesis and transmission of SARS-CoV-2 in this country and analyzed associations of these variations with host factors.

Methodology: In total, 774 SARS-CoV-2 genomic sequences obtained and annotated by the Global Initiative on Sharing All Influenza Data (GISAID) were captured and analyzed.

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Background: Demand for clinical laboratory services in our insti.tution has increased by 7% each year in the past 5 years, while the amount budgeted for services has remained fixed. To address the issue, we conducted a pilot study to curb inappropriate demand by implementing a minimum retest interval (time-based restrictions on the ordering certain tests) and thus reduce costs.

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Article Synopsis
  • A novel H1N1 influenza A virus emerged in Mexico in 2009, spreading globally, with a lack of information about its evolutionary dynamics in Saudi Arabia.
  • Nucleotide sequencing and bioinformatics were used to analyze 72 hemagglutinin and 45 neuraminidase H1N1 gene sequences from Saudi Arabia, revealing circulation of two virus clades, with clade 7 being predominant in 2009.
  • The Saudi isolates were closely related to the A/California/7/2009 vaccine strain, showing new mutations in the HA gene that could affect viral fitness, highlighting the need for ongoing monitoring to identify potential virulent and drug-resistant variants.
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In this report we present a case of a young lady with abdominal abscesses and septicemia caused by Mycobacterium chelonae complex. Identification of the organism and initiation of the appropriate antimicrobial therapy was delayed, resulting in significant morbidity and multiple hospital admissions. Gram staining of these organisms from blood culture can be easily overlooked or confused with either debris or diptheroids.

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