Publications by authors named "Sahar Hassani Afshar"

Article Synopsis
  • Pseudomonas aeruginosa is a dangerous bacteria often found in hospitals that can cause severe infections, especially in patients on ventilators, and its harmful effects are largely due to its type III secretion system (T3SS) and the important protein PcrV.
  • Researchers created a recombinant antibody (scFv) targeting the PcrV protein, using a specific cultivation method (EnBase®) and E. coli to optimize the protein's expression and solubility at varying temperatures and induction times.
  • The study found that this anti-PcrV scFv showed good effectiveness in lab tests, notably offering protection to red blood cells from being damaged by the bacteria.
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