Publications by authors named "Sahar A Fadallah"
Stem Cell Res Ther
October 2024
Article Synopsis
- - Diabetes mellitus (DM) is a major global health issue, and current treatments often do not effectively prevent long-term complications, prompting interest in the use of mesenchymal stem/stromal cells (MSCs) for treatment.
- - MSCs have regenerative properties and can improve diabetes outcomes by enhancing insulin production, reducing insulin resistance, and protecting insulin-producing beta cells, with evidence from animal studies and clinical trials showing positive effects.
- - The review also highlights different strategies to optimize MSC treatment for diabetes, discusses the potential of MSC-derived extracellular vesicles, and addresses challenges like sourcing MSCs and the need for larger clinical trials to better understand their safety and efficacy.
