"Skin Whitening Creams: Cosmetovigilance.".

Cosmeceutical products such as skin-lightening agents have been used globally to enhance skin tone and obtain a magnificent outward appearance. The pigment known as melanin, produced by melanocytes, imparts skin color. The Cosmetic Europe survey testifies that most people believe that cosmetics enhance one's quality of life.

Towards privacy-preserving Alzheimer's disease classification: Federated learning on T1-weighted magnetic resonance imaging data.

Objective: This study aims to address the challenge of privacy-preserving Alzheimer's disease classification using federated learning across various data distributions, focusing on real-world applicability. The goal is to improve the efficiency of classification by minimizing communication rounds between clients and the central server.

Methods: The proposed approach leverages two key strategies: increasing parallelism by utilizing more clients in each communication round and increasing computation per client during the intervals between rounds.

Correlating tissue and plasma‑specific piRNA changes to predict their possible role in pancreatic malignancy and chronic inflammation.

The aggressiveness of pancreatic ductal adenocarcinoma is primarily due to lack of effective early detection biomarkers. Circulating non-coding RNAs serve as diagnostic or prognostic biomarkers in multiple types of cancer. Comparison of their expression between diseased tissue and relevant body fluids such as saliva, urine, bile, pancreatic juice, blood etc.

Second phase CuO boosted photocatalytic activity of fluorine doped CuO nanoparticles.

The photocatalytic activity of fluorine (F) doped CuO nanoparticles (NPs) prepared employing modified sol-gel process was investigated here in this study. Structural and elemental characterization using XRD and XPS data confirmed successful incorporation of F as dopant. F doping led to lattice distortion and reduced crystallinity with smaller crystallite size while promoting the emergence of CuO as the second phase.

Investigating the impact of external application of formalin and potassium permanganate on hematological, immunological, and biochemical profiles in fingerlings.

The present study aimed to elucidate the suitability of formalin and KMnO as therapeutics for fish diseases in Indian major carp, , while considering their impact on fish stress levels. Acute toxicity tests revealed that the 96-hour LC values for formalin and KMnO were 66.58 ppm and 2.

Performance of chest X-ray scoring in predicting disease severity and outcomes of patients hospitalised with COVID-19 in Bangladesh.

Introduction: Evaluation of potential outcomes of COVID-19-affected pneumonia patients using computed tomography scans may not be conceivable in low-resource settings. Thus, we aimed to evaluate the performance of chest X-ray scoring in predicting the disease severity and outcomes of adults hospitalised with COVID-19.

Methods: This was a retrospective chart analysis consuming data from COVID-19-positive adults who had chest X-ray availability and were admitted to a temporary COVID unit, in Bangladesh from 23rd April 2020 to 15th November 2021.

Intraductal papillary neoplasm of the bile duct: A case report of a rare tumor with a brief review of literature.

Introduction And Importance: Intraductal papillary neoplasm of the bile duct (IPNB) is a rare neoplasm, mostly found in patients from far Eastern areas where hepatolithiasis and clonorchiasis are endemic. Very few cases are reported from India.

Case Presentation: We present a case of recurrent cholangitis in a 59-year-old male, initially suspected to have IPNB based on preoperative imaging.

Unveiling the potential anti-cancer activity of calycosin against multivarious cancers with molecular insights: A promising frontier in cancer research.

Background: Calycosin may be a potential candidate regarding chemotherapeutic agent, because already some studies against multivarious cancer have been made with this natural compound.

Aim: This review elucidated a brief overview of previous studies on calycosin potential effects on various cancers and its potential mechanism of action.

Methodology: Data retrieved by systematic searches of Google Scholar, PubMed, Science Direct, Web of Science, and Scopus by using keywords including calycosin, cancer types, anti-cancer mechanism, synergistic, and pharmacokinetic and commonly used tools are BioRender, ChemDraw Professional 16.

Esculetin unveiled: Decoding its anti-tumor potential through molecular mechanisms-A comprehensive review.

Background: The growing complexity of cancer has made it a significant concern in the medical community. Although cancer research has advanced, it is still challenging to create new effective medications due to the limitations and side effects of existing treatment strategies. These are enforcing the development of some alternative drugs from natural compounds with fewer drawbacks and side effects.

Dibenzoheterole-Fused -Indacenes.

Heterole (pyrrole, thiophene, furan, thiophene-,-dioxide)-fused -indacenes are known for their enhanced paratropic ring-current strength. However, the outcome of the antiaromatic properties for dibenzoheterole-fused -indacene antiaromatics remained underexplored. Carbazole-, dibenzothiophene-, dibenzofuran-, and dibenzo[,]thiophene-5,5-dioxide-fused -indacenes -, respectively, were synthesized and characterized by experimental (NMR, single-crystal, UV-vis, CV) and computational (DFT) approaches to study the ground-state antiaromatic properties.

A novel approach in valorization of spent mushroom substrate of Cordyceps militaris as in-feed antibiotics in Labeo rohita against Aeromonas hydrophila infection.

The study was carried out to investigate Cordyceps militaris spent mushroom substrate (CMSMS), a renewable biomass, for its effect on fish as an alternative source of in-feed antibiotics. For meticulous examination, four different iso-nitrogenous and iso-caloric diets were prepared containing CMSMS at 0%, 1%, 2%, and 3%. A total of 360 Labeo rohita fingerlings with an average initial weight and length of 12.

Visible-Light-Induced Metal- and Photocatalyst-Free Radical Cascade Cyclization of Cinnamamides for Synthesis of Functionalized Dihydroquinolinones.

Visible-light-promoted metal- and photocatalyst-free radical cascade cyclization of cinnamamides with α-oxocarboxylic acids is described for sustainable synthesis of diverse pharmaceutically important dihydroquinolinone scaffolds in one pot under mild conditions. The decarboxylative cascade cyclization proceeded efficiently at room temperature without the need for expensive photocatalysts such as Ir or Ru complexes, which indicates the practicability and environmentally benign nature of this protocol. Preliminary mechanistic studies reveal that the blue LED irradiation efficiently cleaves the I-O bond of the hypervalent iodine reagent PhI(OCCOAr) formed through ligand exchange between iodobenzene diacetate and arylglyoxylic acid to initiate the cascade reaction.

Burden, predictors, and outcome of unconsciousness among under-five children hospitalized for community-acquired pneumonia: A retrospective study from a developing country.

Despite the reduction of death from pneumonia over recent years, pneumonia has still been the leading infectious cause of death in under-five children for the last several decades. Unconsciousness is a critical condition in any child resulting from any illness. Once it occurs during a pneumonia episode, the outcome is perceived to be fatal.

Vaccination following the expanded programme on immunization schedule could help to reduce deaths in children under five hospitalized for pneumonia and severe pneumonia in a developing country.

Background: Worldwide, pneumonia is the leading cause of mortality in children under the age of five. An expanded program on immunization (EPI) is one kind of evidence-based tool for controlling and even eradicating infectious diseases.

Objectives: This study aimed to explore the impact of EPI vaccination, including BCG, DPT-Hib-Hep B, OPV, IPV, and PCV-10, among children from the age of 4 to 59 months hospitalized for pneumonia and severe pneumonia.

Factors associated with time to first dialysis-associated peritonitis episode: Data from the Peritonitis Prevention Study (PEPS).

Introduction: Peritonitis remains a potentially serious complication of peritoneal dialysis (PD) treatment. It is therefore important to identify risk factors in order to reduce the incidence of peritonitis. The aim of the present analysis was to identify factors associated with time to first peritonitis episode.

Few-shot deep learning for AFM force curve characterization of single-molecule interactions.

Deep learning (DL)-based analytics has the scope to transform the field of atomic force microscopy (AFM) with regard to fast and bias-free measurement characterization. For example, AFM force-distance curves can help estimate important parameters of binding kinetics, such as the most probable rupture force, binding probability, association, and dissociation constants, as well as receptor density on live cells. Other than the ideal single-rupture event in the force-distance curves, there can be no-rupture, double-rupture, or multiple-rupture events.

A Π-shaped slotted patch antenna with a partial ground structure for lower 5G/WiFi/WiMAX applications.

In this research work, a π-shaped slotted microstrip patch antenna (MPA) with a partial ground structure for lower fifth generation (5G)/wireless fidelity (WiFi)/worldwide interoperability for microwave access (WiMAX) applications is presented. The proposed MPA is optimized and designed by using the computer simulation technology (CST) microwave studio (MWS) suite version of 2018. The π-shaped slotted MPA is mounted on low loss dielectric material Rogers RT5880 with a height of 0.

In-person training on COVID-19 case management and infection prevention and control: Evaluation of healthcare professionals in Bangladesh.

Background: As COVID-19 was declared a global pandemic, the major focus of healthcare organizations shifted towards preparing healthcare systems to handle the inevitable COVID-19 burden at different phases and levels. A series of in-person training programs were operated in collaboration with government and partner organizations for the healthcare workers (HCW) of Bangladesh. This study aimed to assess the knowledge of HCWs regarding SARS-CoV-2 infection, their case management, infection prevention and control to fight against the ongoing pandemic.

A Modular Vision Language Navigation and Manipulation Framework for Long Horizon Compositional Tasks in Indoor Environment.

In this paper we propose a new framework-MoViLan (Modular Vision and Language) for execution of visually grounded natural language instructions for day to day indoor household tasks. While several data-driven, end-to-end learning frameworks have been proposed for targeted navigation tasks based on the vision and language modalities, performance on recent benchmark data sets revealed the gap in developing comprehensive techniques for long horizon, compositional tasks (involving manipulation and navigation) with diverse object categories, realistic instructions and visual scenarios with non reversible state changes. We propose a modular approach to deal with the combined navigation and object interaction problem without the need for strictly aligned vision and language training data (e.

Unveiling two antiaromatic -indacenodicarbazole isomers with tunable paratropicity.

Linear and curved antiaromatic -indacenodicarbazole isomers were synthesized and characterized to show the tunable paratropicity of -indacene, as analyzed by NICS(1) and ACID (ring-current) calculations. The curved isomer showed a greater degree of antiaromaticity than the linear isomer, as predicted by the Glidewell-Lloyd rule. This degree of antiaromaticity was further validated by the red-shifted UV-vis absorption and smaller HOMO-LUMO energy gap.

Prevalence, Predictive Factors, and Outcomes of Respiratory Failure in Children With Pneumonia Admitted in a Developing Country.

Background: Pneumonia has been the leading infectious cause of morbidity and mortality in children under 5 years of age for the last several decades. Although most of these deaths occur due to respiratory failure, published data are limited regarding predicting factors and outcomes of respiratory failure in children hospitalized with pneumonia or severe pneumonia.

Objective: This study aimed to explore the prevalence, predicting factors, and outcomes of respiratory failure in children under-five with pneumonia or severe pneumonia.

Effects of Light Quality on Colonization of Tomato Roots by AMF and Implications for Growth and Defense.

Beneficial soil microbes can enhance plant growth and defense, but the extent to which this occurs depends on the availability of resources, such as water and nutrients. However, relatively little is known about the role of light quality, which is altered during shading, resulting a low red: far-red ratio (R:FR) of light. We examined how low R:FR light influences arbuscular mycorrhizal fungus (AMF)-mediated changes in plant growth and defense using (tomato) and the insect herbivore .

Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management.

Psoriasis is a chronic inflammatory autoimmune disorder that moderately affects social and interpersonal relationships. Conventional treatments for psoriasis have certain problems, such as poor drug penetration through the skin, hyper-pigmentation, and a burning sensation on normal and diseased skin. Colloidal drug delivery systems overcome the pitfalls of conventional approaches for psoriasis therapeutics and have improved patient safety parameters, compliance, and superior effectiveness.