Effect of sedation on soluble P-selectin levels, coagulation and myocardial damage following a coronary intervention.

This study was aimed to investigate the effect of sedation on plasma soluble P-selectin (sP-selectin) levels and initiation phase of coagulation following coronary intervention. A total of 58 patients with unstable angina were randomised into two groups of sedated (n = 29) and nonsedated (n = 29) patients. sP-Selectin, adrenaline, noradrenaline, von Willebrand factor (vWF), fibrinogen, platelet and troponin-I levels were measured before the intervention and at 30 min and 24 h after the intervention.

[The importance of lipoprotein(a) in pathogenesis of the high risk unstable angina].

Objective: The aim of this study is to compare lipoprotein (a) [Lp(a)] levels in patients with low and high risk unstable angina pectoris, which is defined according to the cardiac troponin-I (Tn-I) levels and to investigate their relation with myocardial damage.

Methods: From patients with chest pain; venous blood samples were collected for measuring serum Lp(a) and C-reactive protein (CRP) levels on admission and serum cTn-I levels 12 and 24 hours after admission. Fifty-nine patients with serum cTn-I levels <1.

Effect of irbesartan monotherapy compared with ACE inhibitors and calcium-channel blockers on patient compliance in essential hypertension patients: a multicenter, open-labeled, three-armed study.

Objectives: This multicenter, three-armed, open-labeled study investigated patient compliance of patients receiving irbesartan, angiotensin-converting enzyme (ACE) inhibitors or calcium-channel blockers (CCB) for essential hypertension for a 6-month period. Patients were either newly diagnosed or switched from existing antihypertensive medication due to lack of efficacy or side-effects.

Methods: Patients were started monotherapy with irbesartan (n=377), ACE inhibitors (n=298) or CCB (n=308) and were reevaluated on 1st, 3rd, and 6th months of the treatment.

Bacterial endocarditis of systemic atrioventricular valve (tricuspid valve) in corrected transposition and its surgical treatment.

We describe a case of congenitally corrected transposition of great arteries (CCTGA). Tricuspid valve replacement was performed due to valve dysfunction following bacterial endocarditis. After two weeks' antibiotic therapy haemodynamic stabilisation was obtained and the patient was operated in the third week.

[Is slow coronary flow related with inflammation and procoagulant state?].

Objective: To investigate the pathogenesis of coronary slow flow (CSF), C-reactive protein (CRP) levels as indicator of inflammation and procoagulant activity were studied in patients with CSF.

Methods: Fifty-one patients (22 female, mean age; 53+/-10 years) who were admitted to our clinic with chest pain and had the diagnosis of CSF established by TIMI frame count method and coronary angiography, and 44 healthy subjects (18 female, mean age; 546 years) with normal coronary flow (NCF) were included in the study. Subjects with any infectious and systemic immune disease were excluded from the study.

Hypertrophic cardiomyopathy: a case of symptomatic Japanese type apical hypertrophic cardiomyopathy.

A 61-year-old male patient was hospitalized due to the exertional angina pectoris. A diagnosis of apical hypertrophic cardiomyopathy was made by ECG (electrocardiography), echocardiographic, and coronary angiographic findings. This case was reported and related literature was reviewed because of its similarity to Japanese type apical hypertrophic cardiomyopathy (AHCMP) cases rarely seen outside Asia.

[Plasma insulin, glucose and lipid levels, and their relations with corrected TIMI frame count in patients with slow coronary flow].

Objective: High baseline insulin and glucose levels and presence of accompanying dyslipidemia, which are considered in the pathogenesis of metabolic syndrome X, were also observed in patients with cardiac syndrome X, which is similar to metabolic syndrome X in many aspects. In this study we aimed to compare serum insulin, glucose and lipid levels in patients with coronary slow flow which is hypothesized as a subgroup of cardiac syndrome X with those of healthy subjects and determine the relation of corrected TIMI frame count (cTFC) with these levels.

Methods: Forty-six patients with normal epicardial coronary arteries but determined as coronary slow flow in coronary angiography performed because of chest pain and 16 healthy subjects having normal coronary arteries but without coronary slow flow were included in this study.

Paroxysmal ventricular tachycardia due to interventricular hydatid cyst.

A 35-year-old male patient with palpitations and mild lightheadedness was admitted to our clinic. Short-lasting paroxysmal ventricular tachycardia was diagnosed following 12-lead electrocardiography (ECG). A mass that included two-thirds of the interventricular septum and the left ventricular cavity was seen by two-dimensional echocardiography and magnetic resonance imaging (MRI).

Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography.

Objective: To compare the hemodynamic and sedative effects of midazolam - with or without fentanyl combination - with placebo in coronary angiography.

Design: Prospective, double-blind, randomized study.

Setting: University medical centre.

The effect of aminophylline infusion on the exercise capacity in patients with syndrome X.

Aminophylline was known to decrease effort angina and ischaemia in patients with coronary artery disease and stable angina. This effect has been explained by the antagonization of the vasodilatation caused by adenosine and the prevention of the transmural myocardial maldistribution (steal phenomenon). In this study, treadmill exercise tests (with Bruce protocol) were performed in 14 patients (11 women, 3 men, mean age 51 +/- 9.

The levels of lipids, lipoproteins and apolipoproteins in healthy people in the central region of the Black Sea.

Lipids, lipoproteins and apolipoproteins are among the risk factors for the most serious health problem of the age--coronary artery disease (CAD). They vary from country to country, from area to area within a country, depending on genetic, environmental, dietary and many other factors. Our aim was to determine the levels of lipids, lipoproteins and apolipoproteins in healthy people in the central Black Sea region of Turkey.

A massive calcified left ventricular aneurysm with normal coronary arteries and without myocardial infarction. A case report.

Most cardiac aneurysms develop after myocardial infarction. Calcification in the aneurysmal wall is seen rarely. In this case report the authors present a thirty-nine-year-old man, who had been free from symptoms until eight months before, when he began to experience palpitations due to monomorphic sustained ventricular tachycardia.

Left circumflex coronary artery arising as a terminal extension of right coronary artery. A case report.

Many types of coronary artery anomalies have been detected, and most of them occur in the left circumflex artery. In this report a unique circumflex artery anomaly is presented. The left circumflex artery arose as a terminal extension of the right coronary artery.

Early detection of left ventricular aneurysm rupture by two-dimensional echocardiography and surgical salvage.

A 52-year-old man was admitted to hospital emergency room with cardiogenic shock. The electrocardiogram showed normal tracing. Left ventricular aneurysm rupture at the posterolateral wall and haemopericardium was diagnosed with two-dimensional and colour Doppler echocardiography.