Publications by Sagar C Khedkar

Publications by authors named "Sagar C Khedkar"

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Patent landscape for discovery of promising acyltransferase DGAT and MGAT inhibitors.

Vishal P Zambre Shamali M Khamkar Dnyaneshwar D Gavhane Sagar C Khedkar Monali R Chavan

Expert Opin Ther Pat

November 2020

Introduction: DGAT and MGAT enzymes play an important role in triacylglycerol (TGA) biosynthesis. Overexpression of these enzymes may lead to accumulation of TGA in adipose tissues causing development of diseases such as obesity and diabetes. High triglyceride levels increase risk factors for atherosclerosis, and increase the risk of heart attack, stroke and other heart diseases.

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