Publications by authors named "Safwan Omran"

Background: Peripheral artery disease (PAD) outcomes often rely on the expertise of individual vascular units, introducing potential subjectivity into disease staging. This retrospective, multicenter cohort study aimed to demonstrate the ability of artificial intelligence (AI) to provide disease staging based on inter-institutional expertise by predicting limb outcomes in post-interventional pedal angiograms of PAD patients, specifically in comparison to the inframalleolar modifier in the Global Limb Anatomic Staging System (IM GLASS).

Methods: We used computer vision (CV) based on the MobileNetV2 model, implemented via TensorFlow.

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Background: Vascular graft infection (VGI) is a serious complication after implantation of arterial vascular grafts. Optimal surgical and pathogen-specific antimicrobial treatment regimens for VGI are largely unknown. We evaluated patients with arterial VGI according to onset, location, microbiological and imaging characteristics, and surgical and antimicrobial treatment and performed an outcome evaluation.

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A thoracoabdominal aortic aneurysm (TAAA) can be potentially life-threatening due to its associated risk of rupture. Thoracoabdominal aortic aneurysm repair, performed as endovascular repair and/or open surgery, is the recommended therapy of choice. Hemodynamic instability, severe blood loss, and spinal cord or cerebral ischemia are some potential hazards the perioperative team has to face during these procedures.

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Ischemic hepatitis due to mesenteric artery occlusion is extremely rare. This is due to the function of the collateral network of the celiac-mesenteric arterial system and portal venous flow. A 64-year-old male presented with abdominal pain, a significantly reduced general condition, a weight loss of 20 kg in 4 months.

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(1) Background: This retrospective study evaluated perioperative and intensive care unit (ICU) variables to predict colonic ischemia (CI) after infrarenal ruptured abdominal aortic aneurysm (RAAA) surgery. (2) Materials and Methods: We retrospectively analyzed the data of the patients treated for infrarenal RAAA from January 2011 to December 2020 in our hospital. (3) Results: A total of 135 (82% male) patients were admitted to ICU after treatment of infrarenal RAAA.

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Article Synopsis
  • The study focused on creating a new scoring model (CSI-score) for assessing the severity of mesenteric artery stenosis in patients with chronic mesenteric ischemia (CMI).
  • A total of 242 patients were analyzed, resulting in a scoring system that effectively distinguished between low and high severity cases based on their arterial health, with a significant cut-off point established at a score of 8.
  • The high-score group (≥ 8) demonstrated an increased prevalence of related health issues and a higher likelihood of requiring invasive treatments, highlighting the importance of this scoring model in predicting treatment needs and outcomes for CMI patients.
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Background: Endovascular aortic aneurysm repair (EVAR) has become the standard procedure for treating infrarenal abdominal aortic aneurysms (AAA). Various associated complications can lead to open conversion (OC). Thorough follow-up after the procedure is mandatory for the early detection of complications.

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Objective: To evaluate and compare the outcomes of Candida- and non-Candida-associated aortic graft infections.

Methods: We retrospectively analyzed the data from patients treated for aortic graft infection from 2015 to 2021 in our hospital.

Results: A total of 66 patients (56 men; median age, 69 years; range, 50-87 years) were admitted with aortic graft infection, including 21 (32%) patients in the Candida group and 45 (68%) in the non-Candida group.

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Objective: To report and compare neoaortoiliac system reconstruction and cryopreserved human allograft in treating aortic graft infections.

Methods: We retrospectively analysed the data of the patients treated for aorto graft infections between January 2015 and May 2021 in our hospital. The clinical data, diagnostic procedures, and surgical options were evaluated.

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Objectives: This study's objective was to evaluate Endurant II (Medtronic Inc, Minneapolis, Minnesota) stent graft's early and midterm outcomes and compare the results according to the anatomic severity grade (ASG) scores.

Methods: This was a retrospective study of patients treated with the Endurant II stent graft between January 2013 and May 2021. The patients were divided into 2 independent groups, including those with a low ASG score (score <14) and a high ASG score (score >14).

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Article Synopsis
  • This study compares endovascular treatment (EVT) and open surgery (OS) for visceral artery erosion bleeding after pancreatitis and pancreatic surgery in 65 patients.
  • Key findings showed that EVT had a lower rate of complications and better 30-day survival compared to OS, with significant postoperative morbidity differences.
  • The authors suggest that an endovascular-first approach is preferable for patients who are stable, indicating a need for further research to optimize treatment strategies.
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This study aimed to evaluate risk factors for adverse outcomes and perioperative stroke and death in patients with symptomatic carotid stenosis undergoing open endarterectomy (CEA). The second objective was to assess the predictive value of the POSSUM and V-POSSUM models for predicting morbidity and mortality from CEA in symptomatic carotid stenosis. A retrospective observational study of all patients admitted to a single center who underwent CEA for symptomatic carotid stenosis was performed.

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Article Synopsis
  • This study explored the effectiveness of using a steerable sheath for cannulating renovisceral vessels during complex endovascular procedures for aortic aneurysms from 2016 to 2019.
  • Out of 53 patients, the success rate for cannulation was very high at 99%, with only minimal complications reported, and no significant difference in complications between challenging and nonchallenging vessels.
  • The results indicate that this method is both safe and feasible, with a strong survival rate and vessel patency over a follow-up period of up to three years.
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Article Synopsis
  • * The study collected muscle biopsies from twenty PAD patients to compare VEGF levels in ischemic (gastrocnemius) versus non-ischemic (vastus) muscles before and after surgical or endovascular treatments.
  • * Results showed preoperative VEGF levels were higher in ischemic muscles, but postoperative levels dropped significantly, indicating potential issues with angiogenesis despite revascularization, highlighting the need for further research to improve treatment options for PAD.
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Background: The goal of this study is to investigate the clinical presentation, treatment options, and outcomes of the patients with isolated ruptured paravisceral penetrating aortic ulcers (PV-PAU).

Methods: All patients presenting with acute aortic syndrome from 2015 to 2020 were screened, of which patients with isolated ruptured PV-PAU were included in this retrospective study. Study endpoints were the assessment of treatment options, technical success, and clinical outcome.

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Background: Aortic complications after intravesical Bacillus Calmette-Guérin (BCG) application are a rare complication of the treatment of non-muscle invasive bladder cancer. The aim of this systematic review was to perform a descriptive analysis of previously published studies and to discuss the particular challenges of diagnosis and treatment of this rare complication.

Material And Methods: A literature search was performed in PubMed (1949-2021) and Web of Science (1900-2021) using the search terms "mycobacterium" OR "bovis" OR "BCG" AND "aorta" OR "aneurysm".

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Endovascular repair (EVAR) has become the standard procedure in treating thoracic (TAA) or abdominal aortic aneurysms (AAA). Not entirely free of complications, a persisting perfusion of the aneurysm after EVAR, called Endoleak (EL), leads to reintervention and risk of secondary rupture. How the aortic wall responds to the implantation of a stentgraft and EL is mostly uncertain.

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Objectives: This study's objective was to compare several preoperative and intensive care unit (ICU) prognostic scoring systems for predicting the in-hospital mortality of ruptured abdominal aortic aneurysms (RAAAs).

Design: Retrospective cohort study.

Setting: Single tertiary university center.

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Background: Peripheral arterial disease (PAD) is accompanied by myopathy characterized by mitochondrial dysfunction. The aim of this experimental study was to investigate the effect of revascularization procedures on mitochondrial function in ischemic and non-ischemic muscle.

Methods: Muscle biopsies from patients with symptomatic stage IIB/III PAD caused by isolated pathologies of the superficial femoral artery were obtained from muscle regions within the chronic ischemic muscle (gastrocnemius) and from non-ischemic muscle (vastus lateralis) before and 6 weeks after invasive revascularization.

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Introduction And Importance: Aneurysms of the carotid artery are rare and potentially a risk factor for developing neurological events. This case report describes the treatment of a giant saccular aneurysm of the right extracranial internal carotid artery (ICA) with adhesion to the vagus verve.

Case Presentation: An 85-year-old female presented with an asymptomatic pulsating mass on the right neck.

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Objective: In the present study, we have reported and compared aortoduodenal fistulas (ADFs) after endovascular abdominal aortic aneurysm repair (EVAR) vs after open aortic repair (OAR).

Methods: We retrospectively analyzed the data from patients treated for ADFs from January 2015 to May 2020 in our hospital. The clinical data, diagnostic procedures, and surgical options were evaluated.

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Article Synopsis
  • This study compares the clinical presentation and outcomes of patients with tumor-related (TR) and nontumor-related (NTR) aorto-esophageal (AEF) and aorto-bronchial fistulas (ABF), focusing on thoracic endovascular aortic repair (TEVAR).
  • A review of 16 patients (8 with TR and 8 with NTR) showed that while TEVAR was 100% technically successful, mortality rates were significantly higher in the TR group than in the NTR group at 1 year.
  • The findings suggest that TEVAR is effective for NTR ABFs but should be used more cautiously for TR fistulas due to high mortality rates.
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Objective: To report and analyze the indications and results of endovascular and open surgical treatment for uretero-arterial fistula.

Methods: We retrospectively reviewed the clinical data of 25 consecutive patients with uretero-arterial fistulas admitted to our hospital from 2011 to 2020. Endpoints were technical success, freedom from open conversion, stent-graft/graft-related complications, and 30-day and one-year mortality.

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Objective: Myopathy, characterised by altered mitochondrial function, is a central part of the pathophysiology of peripheral arterial disease and the aim of this study was to investigate the effect of revascularisation on mitochondrial function.

Methods: High resolution respirometry was used to investigate mitochondrial respiration and the results were normalised to citrate synthase activity (CSA), a marker of mitochondrial content. Ten patients with symptomatic peripheral arterial disease (study group) and 10 subjects without ischaemia (control group) were included.

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